Results 61 to 70 of about 1,100,043 (331)
Absence of a consistent classical equation of motion for a mass-renormalized point charge
, 2009 The restrictions of analyticity, relativistic (Born) rigidity, and negligible O(a) terms involved in the evaluation of the self electromagnetic force on an extended charged sphere of radius "a" are explicitly revealed and taken into account in order to ...
A. D. Yaghjian +10 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
IEEE Access, 2018 The now ubiquitous use of information technology poses a crucial challenge to the cyber security of power grid operations, one that has aroused serious concerns from both industry and academia.
Xiaoge Huang, Zhijun Qin, Hui Liu
doaj +1 more source
Identity as a causal power [PDF]
The International Journal of Entrepreneurship and Innovation, 2018 We propose a critical realist-informed conception of entrepreneurial identity – the personal power to create a new venture. Although most people have the power to become an entrepreneur, not everyone can, or is motivated to, realize that potential.
Kasperova, Eva +2 more
openaire +3 more sources
, 2007 We show how rate-distortion theory provides a mechanism for automated theory building by naturally distinguishing between regularity and randomness. We start from the simple principle that model variables should, as much as possible, render the future ...
Crutchfield, James P., Still, Susanne
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Genome Biology, 2020 We propose a new computational framework, probabilistic transcriptome-wide association study (PTWAS), to investigate causal relationships between gene expressions and complex traits.
Yuhua Zhang +8 more
doaj +1 more source
MARS: leveraging allelic heterogeneity to increase power of association testing
Genome Biology, 2021 In standard genome-wide association studies (GWAS), the standard association test is underpowered to detect associations between loci with multiple causal variants with small effect sizes.
Farhad Hormozdiari +3 more
doaj +1 more source