Mendelian randomization analysis of the causal relationship between allergic rhinitis and depression and underlying mediation mechanisms. [PDF]
Zhang S +9 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Bidirectional Mendelian randomization analysis reveals the causal relationship between rheumatoid arthritis and acute sinusitis. [PDF]
Hu R +5 more
europepmc +1 more source
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Research of IT-fraud Threat Using Causal Relationship Diagrams
The study deals with the problem of building causal relationship diagram of insider conduct involving ...
Maxim Andreevich Kalyakin +1 more
core
Genetically Predicted Causal Relationship Between Polycystic Ovary Syndrome and Preeclampsia. [PDF]
Xue G, Zhou X, Zhang H, Wang J, Song X.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Does Bilirubin Have a Causal Relationship With Vitiligo? A Mendelian Randomization Study and Bioinformatics Analysis [PDF]
Danfeng Xu,1 Yinmeng Yin,2 Yan Teng,1 Youming Huang,1 Yong Yu,1 Xiaohua Tao,1 Yibin Fan,1 Xiaoxia Ding1 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital ...
Yin Y +7 more
core
Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study. [PDF]
Liu E +6 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source

