Results 191 to 200 of about 1,626,990 (326)

Genetically predicted the causal relationship between gut-brain axis and chronic pain: a Mendelian randomization study. [PDF]

Hum Genomics
Shi S, Zhou X, Ma C, Wang Y, Deng G, Ma W.   +5 more
europepmc   +1 more source

Investigating bidirectional causal relationships between gut microbiota and insomnia

Shupeng Shi, Dongming Liu, Ancha Baranova, Hongbao Cao, Fuquan Zhang   +4 more
openalex   +1 more source

Unraveling the relationship of loneliness and isolation in schizophrenia: Polygenic dissection and causal inference [PDF]

, 2020
Álvaro Andreu-Bernabeu, Covadonga M. Díaz‐Caneja, Javier Costas, Lucía de Hoyos, C. Stella, Xaquín Gurriarán, Clara Alloza, Lourdes Fañanás, Julio Bobes, Ana González‐Pinto, Benedicto Crespo‐Facorro, Lourdes Martorell, Elisabet Vilella, Gerard Muntané, Juan Nácher, María Dolores Moltó, Eduardo J. Aguilar, Mara Parellada, Celso Arango, Javier González‐Peñas   +19 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Causal relationship between sarcopenia and cognitive performance: A bidirectional Mendelian randomization study. [PDF]

Medicine (Baltimore)
Zhou Y, Guo X, Dong S, Wang C, Wu L, Liu W.   +5 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Causal Relationship Between Butyrate and Dyspepsia: Evidence From Two-Sample Mendelian Randomization Analysis of CSF Metabolites. [PDF]

JGH Open
Cai Y, Jiang Y, Zhou H, Sheng C, Zhu J, Zhu T, Fu G, Fan H.   +7 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Exploring the causal relationship between matrix metalloproteinases and adrenocortical carcinoma: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Huang Z, Zhang Q.
europepmc   +1 more source

Establishing a Causal Relationship Between Intervention to Promote Self-Determination and Enhanced Student Self-Determination

, 2010
Michael L. Wehmeyer, Susan B. Palmer, Karrie A. Shogren, Kendra Williams-Diehm, Jane H. Soukup   +4 more
openalex   +1 more source