Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu +23 more
wiley +1 more source
Modeling non-dual awareness <i>via</i> constraint closure: a reinterpretation of groundlessness. [PDF]
Ward K.
europepmc +1 more source
Rethinking drug safety signal detection and causality assessment in the age of AI: the risks of incomplete data and biased insights [PDF]
Priyanka Chhikara, Tarek A. Hammad
openalex +1 more source
Magnetic Anisotropy Modulation via van der Waals Gap Engineering in 2D Ferromagnet Fe4GeTe2
This study demonstrates a new route to control magnetic anisotropy in 2D ferromagnets via van der Waals gap engineering. In Fe4GeTe2, an interface‐induced vdW gap expansion is found to anomalously enhance in‐plane magnetic anisotropy while suppressing the spin reorientation transition.
Weiran Xie +13 more
wiley +1 more source
Etiological factors of the risk for occupational illness in nursing professionals: An etiology and risk review protocol. [PDF]
Gonzaga CLBDS +7 more
europepmc +1 more source
Research Design in European Studies. Establishing Causality in Europeanization
Nicolás Mariscal
openalex +1 more source
Active restoration increases soil organic carbon stocks by reducing microbial nitrogen limitation. Nitrogen availability promotes particulate to mineral‐associated organic carbon conversion by reducing microbial carbon use efficiency. Passive restoration has no effect on soil organic carbon stocks.
Jinchao Gong +15 more
wiley +1 more source
Genotype-phenotype correlations in 18 European patients with heterozygous <i>KIF1A</i> variants: key considerations for assessing <i>KIF1A</i> variant causality. [PDF]
Uhrova Meszarosova A +15 more
europepmc +1 more source
Personalised information filtering using event causality
Catherine Dolbear, Dolbear, Catherine
openalex +2 more sources
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source

