Results 231 to 240 of about 971,523 (344)

deepTFBS: Improving within‐ and Cross‐Species Prediction of Transcription Factor Binding Using Deep Multi‐Task and Transfer Learning

Advanced Science, EarlyView.
DeepTFBS leverages deep learning to predict transcription factor binding sites across species, integrating multi‐task and transfer learning approaches to improve performance in data‐scarce scenarios. This study demonstrates enhanced accuracy in intra‐ and cross‐species prediction, revealing conserved regulatory patterns and functional variants.
Jingjing Zhai, Yuzhou Zhang, Chujun Zhang, Xiaotong Yin, Minggui Song, Chenglong Tang, Pengjun Ding, Zenglin Li, Chuang Ma   +8 more
wiley   +1 more source

Beyond Correlation: Establishing Causality in Protein Corona Formation for Nanomedicine. [PDF]

Mol Pharm
Rafieioskouei A, Rogale K, Saei AA, Mahmoudi M, Bonakdarpour B.   +4 more
europepmc   +1 more source

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

British medical journal, 2002
D. Wald, M. Law, J. Morris
semanticscholar   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source

Deciphering the causality between micronutrients and esophageal cancer via Mendelian randomization. [PDF]

Nutr Metab (Lond)
Diao Z, Peng G, Chen Y, Wang J, Liu J, Zhang Z, Zhang W.   +6 more
europepmc   +1 more source

Sources of meaning in the acquisition of complex syntax: The sample case of causality

, 1987
Lois Bloom, Joanne Bitetti Capatides
openalex   +2 more sources

Money, Income, and Causality: Some Evidence from Pakistan [PDF]

, 1991
Muhammad Hussain
openalex   +1 more source

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

Sentinel Safety Monitoring System for Adverse Events of Special Interest Associated With Non-NIP Vaccines in Korea. [PDF]

J Korean Med Sci
Hyun H, Heo JY, Choi YJ, Nham E, Yoon JG, Noh JY, Song JY, Kim WJ, Choi WS, Choi MJ, Seo YB, Lee J, Cheong HJ.   +12 more
europepmc   +1 more source

Interpreting Evidence on Money-Income Causality

, 1987
James H. Stock, Mark W. Watson
openalex   +1 more source