Results 81 to 90 of about 264,105 (266)
Quantification of dynamic causal interactions among brain regions constitutes an important component of conducting research and developing applications in experimental and translational neuroscience.
Hristos Courellis +6 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The COVID-19-induced strain on global supply chains led to significant market imbalances and unprecedented inflation, particularly affecting urban economies.
Haibo Wang, Lutfu S. Sua
doaj +1 more source
BİREYSEL EMEKLİLİK ŞİRKETLERİNİN FON YAPILARININ ENFLASYON İLE NEDENSELLİK İLİŞKİSİ
Ülkemizde devlet teşvikiyle büyüme kazanan bireysel emeklilik sistemi bireylerin gelecek yıllardaki ihtiyaçlarını azaltmak adına oldukça önemli bir sistem tamamlayıcısı olmuştur.
Nilüfer Dalkılıç, Mehmet Karataş
doaj
Methods of functional connectivity are applied ubiquitously in studies involving non-invasive whole-brain signals, but may be not optimal for exploring the propagation of the steady-state responses, which are strong oscillatory patterns of neurodynamics ...
Vasily A. Vakorin +9 more
doaj +1 more source
Causal Analysis: Theory and Application [PDF]
Identified opportunities to make statistical analysis more closely approximate the conceptual issues that are apparent in current research in pediatric psychology. The paper proceeds by explicating the logic of multivariate analysis and its application to causal modeling.
openaire +2 more sources
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
In modern industrial processes, it is easier and less expensive to configure alarms by software settings rather than by wiring, which causes the rapid growth of the number of alarms.
Weijun Yu, Fan Yang
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source

