Results 71 to 80 of about 262,504 (266)

Application of Mendelian randomization to explore the genetic association between drinking habits of different beverages and sleep disorder

open access: yesArchives of Medical Science
Introduction This study aimed to provide genetic evidence linking drinking habits of different beverages (DHDB) to sleep disorder liability (SDL), potentially informing clinical treatments to improve lifestyle factors.
Chao Zhang, Xiaoxun Du
doaj   +1 more source

The Impact of Climate Change on Tourism: A Causality Analysis

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2020
Tourism industry is one of the primary sectors that contribute to economic growth of countries worldwide. Since it requires appropriate weather conditions and clean environment, climate changes can significantly affect the sector.
Murat Atasoy, Filiz Guneysu Atasoy
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Does Institutional Quality Shape Agricultural Credit Orientation? Evidence from D-8 Nations

open access: yesAgriculture
The agricultural sector, which has long been overshadowed by industrialization, has reemerged with renewed strategic significance in the face of global crises, including pandemics and armed conflicts.
Ömer Keskin   +3 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The evolutionary traverse: a causal analysis [PDF]

open access: yesJournal of Evolutionary Economics, 2016
This paper explores the process of adaptation to new methods in a simple model where the growth rate of labour supply is exogenously given and constant. It shows that competition for a primary input in short supply changes the mechanism of adaptation and its consequences: If surplus labour exists, differential capacity accumulation effectuates ...
openaire   +2 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source

Generation and Balancing Capacity in Future Electric Power Systems-Scenario Analysis Using Bayesian Networks

open access: yesIEEE Access
This paper examines the evolution of the Finnish electric energy system up to 2035, focusing on the likelihood of different development paths. The primary contribution of this paper is the development of an extensive Bayesian Network, designed to model ...
Seppo Borenius   +3 more
doaj   +1 more source

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