Results 81 to 90 of about 4,282,769 (355)

Pilot-testing a Cancer 101 Education Curriculum with the Fairbanks Native Association’s Women & Children’s Center for Inner Healing [PDF]

, 2014
Cancer is the leading cause of death among Alaska Native people Nevertheless, due to improved detection awareness about cancer prevention, early screening and advances in treatment survival rates are ...
Billings, James, Lopez, Ellen D. S., Villalobos, Ciara, Williams, Freda M.   +3 more
core  

Adult liver transplantation: An analysis of the early causes of death in 40 consecutive cases [PDF]

, 1986
One hundred twenty‐nine adult patients who received an orthotopic liver transplantation and survived at least 24 hr after surgery were evaluated. During the period of follow‐up, 48 of the 129 patients (37%) died.
Calne, Demetris, Dominguez, Dummer, Eggiak, Fennell, Roddy, Schroter, Shaw, Snover, Starzl, Starzl, Starzl, van Thiel, van Thiel, Wajszczuk, Williams, Zajko   +17 more
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Intrapartum fetal deaths and unexpected neonatal deaths in the Republic of Ireland: 2011 – 2014; a descriptive study

BMC Pregnancy and Childbirth, 2018
Background Intrapartum fetal death, the death of a fetus during labour, is a tragic outcome of pregnancy. The intrapartum death rate of a country is reflective of the care received by mothers and babies in labour and it is through analysing these cases ...
K. McNamara, K. O’Donoghue, R. A. Greene   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Transition of the morbidity and mortality profile in a municipality in the interior of the Brazilian Amazon

Revista da Sociedade Brasileira de Medicina Tropical
: INTRODUCTION: The morbidity and mortality profile in a given region reflects its quality of life and provides tools for improving public health policies in that region.
Gabriel de Deus Vieira, Sergio de Almeida Basano, Luís Marcelo Aranha Camargo   +2 more
doaj   +1 more source

Hospital Mortality Rate and Causes of Deaths among the Hospitalized Children in Imam Hossein Children’s Hospital in Isfahan, Iran, during the Years 2012-2017

مجله دانشکده پزشکی اصفهان, 2020
Background: Hospital mortality rate is one of the qualitative indexes, which can be used to assess the quality of care, as well as the mortality patterns in a community.
Mehryar Mehrkash, Rasool Kermani, Royaalsadat Hossienifard, Neda Mostafizadeh, Silva Hovsepian   +4 more
doaj   +1 more source

Has Anyone Ever Died of Old Age? [PDF]

, 2003
The omission of aging as a legal cause of death and the largely unrecognized contribution the aging process plays in mortality is ...
Harry R. Moody, Loeonard Hayflick
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source