Results 61 to 70 of about 2,059,704 (313)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Characteristics and direct causes of death in severely ill patients admitted to a neurology department

Frontiers in Neurology
IntroductionThe study aimed to analyze the characteristics of patients admitted to the neurology department of a tertiary hospital who subsequently died, focusing on those with high disease severity.Materials and methodsWe conducted a retrospective ...
Da Heui Lee, Seok Young Jeong, Byoung-Soo Shin, Byoung-Soo Shin, Hyun Goo Kang, Hyun Goo Kang   +5 more
doaj   +1 more source

Assessing the quality of medical death certification: a case study of concordance between national statistics and results from a medical record review in a regional hospital in the Philippines

Population Health Metrics, 2018
Background Medical certificates of cause of death (MCCOD) issued by hospital physicians are a key input to vital registration systems. Deaths certified by hospital physicians have been implicitly considered to be of high quality, but recent evidence ...
Marilla Lucero, Ian Douglas Riley, Riley H. Hazard, Diozele Sanvictores, Veronica Tallo, Dorothy Gay Marmita Dumaluan, Juanita M. Ugpo, Alan D. Lopez   +7 more
doaj   +1 more source

Cause-of-death data [PDF]

In an earlier note, the value and limitations of mortality data as measures of the health status of a community were discussed. The purpose of this Sixth Note is to extend that discussion and deal specifically with the usefulness to health planners of ...

core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Unsuitable underlying causes of death for assessing the quality of cause-of-death reporting [PDF]

Objectives\u2014This report expands the measures used to evaluate cause-of-death data quality by presenting a novel list of unsuitable underlying causes of death (UCOD).

core  

Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data. [PDF]

, 2011
To describe the likely extent of confounding in evaluating the risks of cardiovascular (CV) events and mortality in patients using diabetes medication. The General Practice Research Database was used to identify inception cohorts of insulin and different
Van Staa, Tjeerd; id_orcid, Leufkens Hubert G. M., Leufkens, Hubert G M, van Staa Tjeerd P., Hubert G M Leufkens, Gallagher, Arlene M, Leufkens, Hubert GM, Smeeth Liam, Suzie Seabroke, Tjeerd P van Staa, Liam Smeeth, Seabroke Suzie, Smeeth, Liam, Arlene M Gallagher, Seabroke, Suzie, Arlene M. Gallagher, Gallagher Arlene M., van Staa, Tjeerd P, Hubert G. M. Leufkens, Tjeerd P. van Staa   +19 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Studying the Degree of Diagnostic Agreement between Medical Records and Death Certificates in Loghman Hospital in 2005

مجله اپیدمیولوژی ایران, 2007
Background & Objectives: There is little doubt about the importance of accurate statistics and reliable information in the promoting community health and optimizing health care.
A Akbarzadeh Bagheban, E Maserat, M Hemmati   +2 more
doaj  

Fatality from COVID-19 does not affect palliative care duration among patients with advanced cancer: a retrospective cohort study [PDF]

Einstein (São Paulo)
Objective: This study aimed at investigating the extent to which COVID-19-induced fatalities affect the duration of palliative care among patients with advanced cancer.
Rafael Tavares Jomar, Jéssica Thaís Nascimento Marques, Livia Costa de Oliveira, Gelcio Luiz Quintella Mendes, Daianny Arrais de Oliveira da Cunha, Raphael Mendonça Guimarães   +5 more
doaj   +1 more source