Results 81 to 90 of about 2,059,704 (313)

Cause of fetal death : data from the Fetal Death Report, 2014 [PDF]

Objectives: This report presents, for the first time, data on cause of fetal death by selected characteristics such as maternal age, Hispanic origin and race, fetal sex, period of gestation, and birthweight.Methods: Descriptive tabulations of data ...

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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Intrapartum fetal deaths and unexpected neonatal deaths in the Republic of Ireland: 2011 – 2014; a descriptive study

BMC Pregnancy and Childbirth, 2018
Background Intrapartum fetal death, the death of a fetus during labour, is a tragic outcome of pregnancy. The intrapartum death rate of a country is reflective of the care received by mothers and babies in labour and it is through analysing these cases ...
K. McNamara, K. O’Donoghue, R. A. Greene   +2 more
doaj   +1 more source

An integrated approach to cause-of-death analysis: cause-deleted life tables and decompositions of life expectancy [PDF]

This article integrates two methods that analyze the implications of various causes of death for life expectancy. One of the methods attributes changes in life expectancy to various causes of death; the other method examines the effect of removing deaths
Samuel Preston, Hiram Beltran-Sanchez, Vladimir Canudas-Romo   +2 more
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Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Consistency between death certificates and hospital records: a study from Kerman University of Medical Sciences

Payesh, 2011
Objective(s): To determine consistency between death certificate and medical records in two hospitals in Kerman, Iran. Methods: Check list was used to collate data on hospital medical records and a questionnaire from viewpoint of certifiers.
Manijeh Ariaei, Eshagh Dortag, Narges Naderi, Rahil Ebrahimi   +3 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Accuracy of Death Certificates for Children: A Population-Based Retrospective Analysis

Pediatric Reports
Background/Objective: Accurate determination and documentation of causes of death in children are essential for generating reliable mortality statistics and guiding public health strategies.
Masahito Yamamoto, Masahito Hitosugi, Eisuke Ito, Kohei Takashima, Mami Nakamura, Seiro Narumiya, Yoshihiro Maruo   +6 more
doaj   +1 more source

Results and observations from the reconstruction of continuous time series of mortality by cause of death [PDF]

Though many countries have been collecting cause-of-death information from death certificates for more than a century, these valuable data sources remain underexplored.
Markéta Pechholdová
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