Results 71 to 80 of about 2,059,704 (313)

Revisiting the mortality of France and Italy with the multiple-cause-of-death approach [PDF]

open access: yes
In this paper, we use the multiple cause-of-death approach to compare the mortality profiles of France and Italy in 2003. Our analysis leads to a substantial re-evaluation of the role played by certain conditions in the process leading to death ...
Aline Desesquelles   +6 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Quality of death notification forms in North West Bank/Palestine: a descriptive study

open access: yesBMC Research Notes, 2017
Background The death notification forms (DNFs) are important documents. Thus, inability to fill it properly by physicians will affect the national mortality report and, consequently, the evidence-based decision making.
Jamal A. S. Qaddumi   +3 more
doaj   +1 more source

Infant death investigation : guidelines for the scene investigator [PDF]

open access: yes
The Guidelines for the Scene Investigator is a 39-page, 5x7 informational handbook that guides investigators in conducting an infant death investigation using recommended practices.

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Transition of the morbidity and mortality profile in a municipality in the interior of the Brazilian Amazon

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
: INTRODUCTION: The morbidity and mortality profile in a given region reflects its quality of life and provides tools for improving public health policies in that region.
Gabriel de Deus Vieira   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Consistency Assessment for the Causes of Death as Indicated in the Death Certificates and in ICD Codes

open access: yesHaseki Tıp Bülteni, 2014
Aim: In this study, we evaluated the consistency between the records made in the hospital automation system as well as the causes of death in the death certificates.
Tanzer Korkmaz, Burçin Balaban
doaj   +1 more source

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