Results 51 to 60 of about 1,867,740 (266)
India and the problem of “needless autopsies”
Egyptian Journal of Forensic Sciences, 2018 The primary aim of autopsy is to ascertain the cause of death. The autopsies performed worldwide are mostly medico-legal or clinical. In India, 'needless autopsies' are conducted widely causing waste of already limited resources.
Tanuj Kanchan +3 more
doaj +1 more source
Competing causes of death: A death certificate study [PDF]
Journal of Clinical Epidemiology, 1997 Despite the widespread interest in competing causes of death, empirical information on interrelationships between causes of death is scarce. We have used death certificate information to estimate the prevalence of competing causes of death at the moment of dying from specific underlying causes of death.In a stratified sample of 5975 deaths occurring in
Mackenbach, J. P. +4 more
openaire +4 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Frontiers in NeurologyIntroductionThe study aimed to analyze the characteristics of patients admitted to the neurology department of a tertiary hospital who subsequently died, focusing on those with high disease severity.Materials and methodsWe conducted a retrospective ...
Da Heui Lee +5 more
doaj +1 more source
Population Health Metrics, 2018 Background Medical certificates of cause of death (MCCOD) issued by hospital physicians are a key input to vital registration systems. Deaths certified by hospital physicians have been implicitly considered to be of high quality, but recent evidence ...
Marilla Lucero +7 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
مجله اپیدمیولوژی ایران, 2007 Background & Objectives: There is little doubt about the importance of accurate statistics and reliable information in the promoting community health and optimizing health care.
A Akbarzadeh Bagheban +2 more
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