Results 181 to 190 of about 2,938,549 (351)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Evolution of causes of death in maintenance hemodialysis patients and the influencing factors： a single-center study

Linchuang shenzangbing zazhi
ObjectiveTo investigate changes in the causes of death among maintenance hemodialysis （MHD） patients over eight years， and to analyze associated risk factors， thus providing theoretical support for reducing the mortality in this population ...
Ye Zi-ling, Yang Fu-yan, Liu Yu-chen, Lu Xu-ke   +3 more
doaj  

Yabunonaka(3)-Takehiro’s Cause of Death and Relationship with Masago-

, 2016
kamyounghee
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The burden of disease and cause of mortality in Ethiopia, 2000–2016: findings from the Global Burden of Disease Study and Global Health Estimates

Studia Medyczne, 2020
Samuel Dessu, Tadele Girum, Mulugeta Geremew, Bereket Zeleke   +3 more
doaj   +1 more source

Study on causes of death and influencing factors in hemodialysis patients with End-Stage renal disease. [PDF]

BMC Urol
Huang J, Li Y, Shen S, Yu L, Sun Q.
europepmc   +1 more source

Is Pickelhaube Sign Really the Hallmark of Arrhythmogenic MVP in Athletes? And Does MVP Really Cause Sudden Death? A Case Report

, 2020
Masimo Bolognesi
openalex   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Prospective systematic classification of causes of death in the course of multiple myeloma. [PDF]

Blood Cancer J
Jin JX, Besemer B, Yilmaz B, Hänel M, Fenk R, Bertsch U, Gu KJ, Hanoun C, Blau IW, Mann C, Scheid C, Schroers R, von Metzler I, Hensel M, Klein EM, Hoffmann M, Lutz C, Riesenberg H, Martens UM, Michel CS, Kunz C, Shumilov E, Gezer D, Holderried TAW, Trautmann-Grill K, Müller-Tidow C, Weisel KC, Raab MS, Salwender HJ, Goldschmidt H, Mai EK.   +30 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source