Results 191 to 200 of about 2,938,549 (351)
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Transformation and causes of death in follicular lymphoma: A Finnish nationwide population-based study. [PDF]
Kalashnikov I +6 more
europepmc +1 more source
Survival and Death Causes in Differentiated Thyroid Carcinoma [PDF]
C. F. A. Eustatia‐Rutten +5 more
openalex +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Adaptive modelling approach for predicting causes of death: insights from verbal autopsy data in Tanzania. [PDF]
Tunga M, Chambua J, Lungo J.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Leading causes of death rankings among U.S. adolescents by race and ethnicity: A comparison of two classification schemes. [PDF]
Tai SY +5 more
europepmc +1 more source

