Results 221 to 230 of about 2,938,549 (351)

Datix for Deaths Due to Physical Health Causes Outside Mental Health Inpatient Settings: Staff Perspective [PDF]

Uchechukwu Egbuta, Manorama Bhattarai, Eimear Devlin   +2 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Causes of death after surgery among cancer patients: a population-based cohort study. [PDF]

Int J Surg
Hao Y, Liang C, Zhang Y, Huang X, Zhao Z, Zhang F, Ruan S, Nie RC, Li Y, Zheng Y, Zhao B.   +10 more
europepmc   +1 more source

Trends in mortality from deep vein thrombosis and pulmonary embolism as multiple causes of death in u.S. adults aged ≥65 years (1999–2023): A CDC wonder analysis [PDF]

Hakim Wazir, Awais Amjad, Krishna Shah, Nayanika Tummala, Shalin Rawal, Adnan Sharif, Arun Chauhan, Minahil Zaheer, Abdul Majid, Shaheen Nawaz, Noora Inam, Vedant Shah, Bolivia Fernandes, Nirmit Patel, Love Kumar   +14 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Causes of Death and Comorbidities in Adult Patients With Late-Onset Pompe Disease: A French Pompe Registry Retrospective Study. [PDF]

Eur J Neurol
Chitimus DM, Tard C, Fournier M, Bouhour F, Béhin A, Salort-Campana E, Lagrange E, Kaminsky AL, Magot A, Beltran S, Noury JB, Magy L, Solé G, Renard D, Spinazzi M, Demurger F, Cintas P, Nadaj-Pakleza A, Deibener-Kaminsky J, Bassez G, Taouagh N, Arrassi A, Lefeuvre C, Attarian S, Hamroun D, Laforêt P, for French Pompe study group.   +26 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Causes of Death in Anti-IgLON5 Disease: A Novel Case Report and Systematic Literature Review. [PDF]

Brain Sci
Howischer T, Gattermeyer-Kell L, Hirschbichler S, Seifert-Held T, Bräsen JH, Katschnig-Winter P, Kögl M, Franthal S, Enzinger C, Höftberger R, Schwingenschuh P.   +10 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Causes of Death in Childhood Acute Lymphoblastic Leukemia: A Single-Center Experience. [PDF]

Medicina (Kaunas)
Jelić M, Pavlović M, Mucavac L, Dejanović Bekić S, Šalek Z, Matić T, Turudić D, Lovrenčić L, Roganović J, Bilić E.   +9 more
europepmc   +1 more source