Results 71 to 80 of about 2,938,549 (351)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
RECONSTRUCTION OF THE CONTINUITY OF CAUSE-SPECIFIC MORTALITY TRENDS FOR THE REPUBLIC OF MOLDOVA [PDF]
Economy and Sociology, 2015 The paper presents the stages of reconstruction of the continuity of cause-of-death time series for Moldova based on a special method developed by French demographers Jacques Vallin and France Meslé (Institut national d’études démographiques, INED).
Olga PENINA
doaj
BMC Women's Health, 2018 Background The aim of this study was to determine whether intrahepatic cholestasis of pregnancy (ICP) is associated with causes of death during on average 35 years follow-up after the delivery. Methods The study population comprised 571 women with ICP in
Suvi-Tuulia Hämäläinen +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Journal of High Institute of Public Health, 2009 Background: Death rarely results from a single cause; it can be caused by a variety of factors. Multiple causes of death (MCD) can provide information about the associations between causes of death revealing common combinations of conditions.
Kamel Alsaleh +4 more
doaj +1 more source
Methodological aspects of constatation of Alzheimer disease as a cause of death in the elderly
Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2020 In connection with the increase in the proportion of the elderly population, the multifaceted adverse significance of Alzheimer’s disease has recently been widely discussed, including its role as a cause of death.
N. G. Neznanov, L. S. Kruglov
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Assessment of the Data Quality of Cause of Death Registration in Iranian Hospitals in 2016
مجله اپیدمیولوژی ایران, 2020 Background and Objectives: A large proportion of the data of cause of death is registered in hospitals in Iran. Assessment of the death data can help to identify the problems of cause of death registration system and improve it. Therefore, this study was
S Aghamohamadi +3 more
doaj
Myocardial fibrosis in stroke survivors [PDF]
, 2015 Stroke survivors are most likely to die of cardiac death, yet few undergo comprehensive cardiac assessment to look for reversible causes. Myocardial fibrosis (MF) is not only the hallmark of cardiomyopathy, but also a substrate for sudden cardiac death ...
Allgar, V. +6 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source