Results 71 to 80 of about 24,469,413 (266)

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source

Automated segmentation of postsurgical resection cavities on magnetic resonance imaging in focal epilepsy: A Multicentre Epilepsy Lesion Detection study

Epilepsia, EarlyView.
Abstract Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative magnetic resonance imaging (MRI). Current methods for resection cavity masking are time‐consuming and labor‐intensive, and existing automated approaches exhibit variable segmentation ...
Jieun Seo, Mathilde Ripart, Helene Kaas, Cornelius Kronlage, Ben Sinclair, Lucy Vivash, Merran R. Courtney, Terence J. O'Brien, Siby Gopinath, Harilal Parasuram, Sedat Kandemirli, Natally Alarab, Lillian Lai, Marcus Likeman, Kai Zhang, Jiajie Mo, Georgian Ciobotaru, James Galea, Philip Sequeiros‐Peggs, Khalid Hamandi, Hua Xie, Venkata Sita Priyanka Illapani, William D. Gaillard, Nathan T. Cohen, Alexander G. Weil, Florence Henrichon‐Goulet, Kenza S. Lahlou, Aristides Hadjinicolaou, Agustín Ibáñez, Gonzalo M. Rojas‐Costa, Horst Urbach, Lara Bücheler, Marcel Heers, Adrián Valls Carbó, Rafael Toledano, Giulia Nobile, Costanza Parodi, Domenico Tortora, Alessandro Consales, Antonella Riva, Mariasavina Severino, Martin Tisdall, Felice D'Arco, Kshitij Mankad, Aswin Chari, Maria H. Eriksson, Rory J. Piper, J. Helen Cross, Torsten Baldeweg, Sofia González‐Ortiz, Jose Pariente, Nuria Bargalló, Yawu Liu, Reetta Kälviäinen, Carmen Barba, Matteo Lenge, Renzo Guerrini, Masaki Iwasaki, Daichi Sone, Hiroyuki Maki, Tomoki Imokawa, Noriko Sato, Julien Jung, Francisco Sepulveda, Daniel Mansilla, Andres Goycoolea, Ingeborg Lopez, Antonio Napolitano, Alessandro De Benedictis, Luca De Palma, Maria Camilla Rossi‐Espagnet, Nikolaos Kondylidis, Kostakis Gkiatis, Kyriakos Garganis, Joshua Pepper, Stefano Seri, John S. Duncan, Clarissa L. Yasuda, Lucas Scárdua‐Silva, Marina K. M. Alvim, Fernando Cendes, Antonio G. Gennari, Ruth O'Gorman Tuura, Georgia Ramantani, Mariam Josyula, Joel Stein, Nishant Sinha, Kate Davis, R. Edward Hogan, Luigi Maccotta, Sophie Adler, Konrad Wagstyl   +91 more
wiley   +1 more source

Seismic Fragility of Gravity and Semi‐Gravity Retaining Walls and Its Impact on the Functionality Loss of Road Infrastructures

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Retaining walls are key geotechnical components of road infrastructure, whose seismic performance directly affects the resilience of transportation networks. Despite their importance, seismic fragility models for retaining walls available in the literature refer only to specific case studies.
Amendola C., Conti R., de Silva F.
wiley   +1 more source

The evaluation of the caveolin-1 and AT-rich interactive domain 1 alpha expressions in uterine smooth muscle tumors

Indian Journal of Pathology and Microbiology, 2016
Objectives: This retrospective study was designed to evaluate the importance of tissue expressions of caveolin-1 (Cav-1) and AT-rich interactive domain 1 alpha (ARID-1A) which are known as signal regulator and tumor suppressor in differential diagnosis ...
Duygu Ayaz, Gulden Diniz, Dudu Solakoglu Kahraman, Sevil Sayhan, Melek Uncel, Tugba Karadeniz, Muzaffer Sanci   +6 more
doaj   +1 more source

Directionality Scaling of Scalar and Vector Ground Motion Intensity Measures

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT The azimuthal directionality of earthquake ground‐motion intensity measures (IMs) is conventionally described by the ratios between the orientation‐independent maximum (RotD100) and median (RotD50) values over the horizontal plane. This study presents a refined characterization of the directionality of 31 IMs, including spectral accelerations (
Mao‐Xin Wang, Gang Wang
wiley   +1 more source

Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature

Pulmonary Circulation, 2019
Caveolin-1 (cav-1) has been shown to play a significant role in the pathogenesis of pulmonary hypertension (PH). In the monocrotaline model of PH, the loss of endothelial cav-1 as well as reciprocal activation of proliferative and anti-apoptotic pathways
Jing Huang, Maria Frid, Michael H. Gewitz, John T. Fallon, Dale Brown, Greta Krafsur, Kurt Stenmark, Rajamma Mathew   +7 more
doaj   +1 more source

Peptidomimetic Targeting of Ca _v β2 Overcomes Dysregulation of the L-Type Calcium Channel Density and Recovers Cardiac Function [PDF]

Circulation, 2016
Background: L-type calcium channels (LTCCs) play important roles in regulating cardiomyocyte physiology, which is governed by appropriate LTCC trafficking to and density at the cell surface. Factors influencing the expression, half-life, subcellular trafficking, and gating of LTCCs are therefore critically involved in ...
Rusconi F, Ceriotti P, Miragoli M, Carullo P, Salvarani N, Rocchetti M, Di Pasquale E, Rossi S, Tessari M, Caprari S, Cazade M, Kunderfranco P, Chemin J, Bang ML, Polticelli F, Zaza A, Faggian G, Condorelli G, Catalucci D   +18 more
openaire   +7 more sources

An Intensity Measure‐Based Methodology for Ground Motion Orientation in Seismic Structural Assessment

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT In current dynamic time history assessment protocols, ground motion recordings are mostly oriented along fixed sensor directions. Consequently, the orientation of the principal resultant of rupture energy, which may control the maximum structural demand, remains undefined, precluding consistent correlation with physically detrimental ...
Santiago Londono‐Lopez, Raffaele Cucuzza, Fabrizio Mollaioli, Giuseppe Carlo Marano, Marco Domaneschi   +4 more
wiley   +1 more source

Molecular detection of canine viral infectious diseases in China: an investigation from 2018 to 2024

Frontiers in Veterinary Science
To analyze the prevalence of canine viral diseases in China, including canine parvovirus type 2 (CPV-2), canine coronavirus (CCoV), canine distemper virus (CDV), canine herpesvirus type 1 (CHV-1), canine parainfluenza virus (CPIV), canine influenza virus
Caihong Liu, Caihong Liu, Caihong Liu, Yalei Chen, Yalei Chen, Ningning Cui, Ningning Cui, Yihang Yang, Yihang Yang, Hangtian Ding, Hangtian Ding, Hongchao Wu, Hongchao Wu, Yuxiu Liu, Yuxiu Liu, Kegong Tian, Kegong Tian, Xingang Xu   +17 more
doaj   +1 more source

Periodic Mechanical Stress Stimulates Cav-1-Dependent IGF-1R Mitogenic Signals in Rat Chondrocytes Through ERK1/2

Cellular Physiology and Biochemistry, 2018
Background/Aims: The biological effects of periodic mechanical stress on the mitogenesis of chondrocytes have been studied extensively over the past few years.
Kewei Ren, Jilei Tang, Xuefeng Jiang, Huiqing Sun, Luming Nong, Nan Shen, Yanqing Gu   +6 more
doaj   +1 more source