Results 51 to 60 of about 24,469,413 (266)

CAV-1 reduces inflammatory activity and then protects tubular nephrocalcinosis and pyelonephritis.

, 2016
(A) CAV-1 is well-distributed in the glomerulus (upper). Staining intensity was higher in the AP-CAV-1-treated rabbits (the HCAV-1 group) than in the untreated hypercholesterolemic rabbits (the HC group).
Ya-Hui Chen (514335), Yueh-Min Lin (297900), Wei-Wen Lin (514336), Chin-San Liu (171255), Li-Sung Hsu (514337), Shih-Li Su (514338)   +5 more
core   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

CAV-1 preserves mitochondrial morphology and reduces mitochondrial biogenesis.

, 2016
(A) A significantly high mtDNA copy number per cell was observed in the HC group than in the NC and HCAV-1 groups. (B) Electron microscopy revealed a darker matrix and integrated mitochondrial membranes after CAV-1 treatment (magnification 20000×, n = 6 ...
Ya-Hui Chen (514335), Yueh-Min Lin (297900), Wei-Wen Lin (514336), Chin-San Liu (171255), Li-Sung Hsu (514337), Shih-Li Su (514338)   +5 more
core   +1 more source

At the edge of change: Native Phragmites persistence and nonnative arrival along the dam‐regulated Colorado River

American Journal of Botany, EarlyView.
Abstract Premise The southwestern United States is at the forefront of nonnative Phragmites australis subsp. australis expansion. Native Phragmites australis subsp. americanus, likely in decline in North America, is ecologically and culturally important and of conservation interest. In the greater Grand Canyon region, the Glen Canyon Dam led to loss of
Emily C. Palmquist, Joel B. Sankey, Claudia DiMartini, Tayan Benson, Brooke Damon, Helen Fairley, Bradley J. Butterfield   +6 more
wiley   +1 more source

Downregulation of RAB7 and Caveolin-1 increases MMP-2 activity in renal tubular epithelial cells under hypoxic conditions

Open Medicine, 2021
Tubulointerstitial fibrosis leads to tubular basement membrane thickening and accumulation of interstitial extracellular matrix (ECM). Matrix metallopeptidase-2 (MMP-2) is involved in the breakdown of ECM.
Yu Wenmin, Ke Xiumei, Li Meiren, Ye Ping, Peng Jing, Li Huimin   +5 more
doaj   +1 more source

Molecular methods for differentiating Phragmites australis subspecies and identification of hybrid stands in the Upper Midwestern United States

Applications in Plant Sciences, EarlyView.
Abstract Premise In North America, Phragmites australis (common reed) has drawn a great deal of research attention. Non‐native P. australis subsp. australis is a noxious weed that has locally displaced native P. australis subsp. americanus in some areas.
Nicholas P. Tippery, Daniel J. Larkin, Julia Bohnen, Douglas L. Wendell, Neil O. Anderson, Susan M. Galatowitsch, Marie Abbey, Alan G. Smith, Andrzej K. Noyszewski   +8 more
wiley   +1 more source

Antibody Titer Testing in Dogs: Evaluation of Three Point-of-Care Tests for Canine Core Vaccine Antigens Compared to Virus Neutralization

Veterinary Sciences
Antibody titer testing can be useful in controlling successful puppy immunization and can reduce unnecessary vaccinations in adult dogs. We evaluated three commercially available point-of-care tests (POCTs) for detecting antibodies against canine ...
Lena Janowitz, Ahmed Abd El Wahed, Uwe Truyen, Regina Hofmann-Lehmann, Andrea Monika Spiri   +4 more
doaj   +1 more source

CHICKEN ANAEMIA VIRUS IMPAIRS NITRIC OXIDE PRODUCTION IN HD11 CHICKEN MACROPHAGES

Slovenian Veterinary Research, 2020
Immunosuppressive viruses cause substantial economic losses to the poultry industry. Chicken anaemia virus (CAV) causes severe disease in young chickens, whereas subclinical infection in older birds causes immunosuppression.
Katja Ester, William Lauman Ragland
doaj   +1 more source

Impact of E1 and Cre on Adenovirus Vector Amplification: Developing MDCK CAV-2-E1 and E1-Cre Transcomplementing Cell Lines

PLoS ONE, 2013
Adenovirus vectors have been extensively studied through the manipulation of viral genome. However, little attention is being paid to their producer cell-lines; cells are selected according to virus yields, neglecting the expression profile of transcomplementing gene products underlying cell performance.
Fernandes, P., Santiago, V. M., Rodrigues, A. F., Tomas, H., Kremer, E. J., Alves, P. M., Coroadinha, A. S.   +6 more
openaire   +5 more sources

CAV-1 enhances SOD2 and catalase protein expressions.

, 2016
(A) Significantly increased expression of mitochondrial antioxidant enzymes SOD2 (upper) and catalase (lower) were observed in the CAV-1-treated hypercholesterolemic rabbits. (B) Quantification of SOD2 and catalase.
Ya-Hui Chen (514335), Yueh-Min Lin (297900), Wei-Wen Lin (514336), Chin-San Liu (171255), Li-Sung Hsu (514337), Shih-Li Su (514338)   +5 more
core   +1 more source