Results 151 to 160 of about 477,524 (311)

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Cave microbial communities are structured by environmental matrix and depth and can be characterized with field-portable assays. [PDF]

Appl Environ Microbiol
Weingarten EA, Fernando BM, Freitas MR, Indest KJ.   +3 more
europepmc   +1 more source

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Habitat Specialization and Airborne Dispersal Shape the Microbiome of a Gypsum Karst Cave. [PDF]

Microb Ecol
Martin-Pozas T, Fernandez-Cortes A, Calaforra JM, Ledesma-Hernandez G, Cuezva S, Sanchez-Moral S, Saiz-Jimenez C, Jurado V.   +7 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Cave reservoir characterization method driven by GA-KPCA and geological knowledge. [PDF]

PLoS One
Ren W, Chen H, Wang R, Zhang T, Li L.
europepmc   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Correction: Curated character of the Initial Upper Palaeolithic lithic artefact assemblages in Bacho Kiro Cave (Bulgaria). [PDF]

PLoS One
Tsanova T, Delvigne V, Sirakova S, Anastasova E, Horta P, Krumov I, Marreiros J, Nacheva E, Rezek Z, Hublin JJ, Sirakov N.   +10 more
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

Prediction of Suitable Habitats for <i>Bisetocreagris</i> (Pseudoscorpiones: Neobisiidae) in China and Its Application in Conserving Endemic Species Diversity. [PDF]

Ecol Evol
Liu S, Li Y, Xie F, Li Y, Wei Z, Yang D, Shi A.   +6 more
europepmc   +1 more source