The complex origin of
Background The loss of phenotypic characters is a common feature of evolution. Cave organisms provide excellent models for investigating the underlying patterns and processes governing the evolutionary loss of phenotypic traits.
Gross Joshua B
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The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Biology of cave crickets, Hadenoecus subterraneus, and camel crickets, Ceuthophilus stygius (Insecta: Orthoptera): Metabolism and water economies related to size and temperature [PDF]
1. 1. Metabolic rate (MR) and water budget (WB) components of cave and camel crickets are directly related to size and temperature.2. 2. MR increases most rapidly with size for insects in general followed by cave crickets (females > males), and lastly,
Lavoie, Kathleen H., Studier, Eugene H.
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Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen +8 more
wiley +1 more source
Selaginella daozhenensis, a new species of the lycophyte genus Selaginella (Selaginellaceae) from a limestone cave in northern Guizhou, China is described and illustrated. The new species is morphologically most similar to S. labordei and S.
Zhao, Jun-Hua +3 more
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The subterranean fauna of a biodiversity hotspot region - Portugal: an overview and its conservation [PDF]
An overview of the obligate hypogean fauna in Portugal (including Azores and Madeira archipelagos) is provided, with a list of obligated cave-dwelling species and subspecies, and a general perspective about its conservation.
Reboleira Ana Sofia P.S. +4 more
doaj
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
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Cave Biology Research Intern/Vernal Pool Research Intern at The University of the South
Cave Biology Research Intern/Vernal Pool Research Intern at The University of the SouthEnvironmental Studies Internship Fund,Drs.Kirk Zigler & Deborah & McGrath, Dept.
Wakefield, Katie
core
The cave bear’s hibernation: reconstructing the physiology and behaviour of an extinct animal
When studying an extinct species such as the cave bear (Ursus spelaeus ROSENMÜLLER 1794), it is possible to apply a variety of molecular biology techniques such as the study of stable isotopes or mitochondrial DNA (mDNA) to infer patterns of behaviour ...
Grandal-d'Anglade A. +3 more
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