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Caveolin‐1 expression in Schwann cells [PDF]
Glia, 1999 Caveolae are non-clathrin-coated invaginations of the plasma membrane, which are present in most cell types. An integral component of caveolae is the caveolin family of related proteins, which not only forms the structural framework of caveolae, but also likely subserves its functional roles, including regulation of signal transduction and cellular ...
Mikol, Daniel D. +3 more
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Caveolin-1 Is Essential for Liver Regeneration
Science, 2006Liver regeneration is an orchestrated cellular response that coordinates cell activation, lipid metabolism, and cell division. We found that caveolin-1 gene–disrupted mice ( cav1 –/– mice) exhibited impaired liver regeneration and ...
Fernandez, Manuel A. +9 more
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Medical Microbiology and Immunology, 2013
Caveolin-1 is one of the major constituents of caveolae. Both Cav-1 and PrP are plasma membrane proteins, which show active capacities for molecular interactions with many other proteins or agents, including themselves. Using yeast two-hybrid system and immunoprecipitation, we reconfirmed the molecular interaction between human Cav-1 and PrP.
Qi, Shi +11 more
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Caveolin-1 is one of the major constituents of caveolae. Both Cav-1 and PrP are plasma membrane proteins, which show active capacities for molecular interactions with many other proteins or agents, including themselves. Using yeast two-hybrid system and immunoprecipitation, we reconfirmed the molecular interaction between human Cav-1 and PrP.
Qi, Shi +11 more
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Caveolin‐1 in oncogenic metabolic symbiosis
International Journal of Cancer, 2020Metabolic phenotypes of cancer cells are heterogeneous and flexible as a tumor mass is a hurriedly evolving system capable of constant adaptation to oxygen and nutrient availability. The exact type of cancer metabolism arises from the combined effects of factors intrinsic to the cancer cells and factors proposed by the tumor microenvironment.
Martina Raudenska +3 more
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Isoforms of caveolin-1 and caveolar structure
Journal of Cell Science, 2000ABSTRACT The relationship between caveolin-1 isoforms (α and β) and caveolar ultrastructure was studied. By immunofluorescence microscopy of human fibroblasts, caveolae were observed as dots positive for caveolin-1, but many dots labeled by an antibody recognizing both isoforms (anti-αβ) were not labeled by another antibody specific for ...
T, Fujimoto, H, Kogo, R, Nomura, T, Une
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Caveolae and caveolin-1 in reptilian liver
Micron, 2011Caveolae are plasma-membrane invaginations that, by interacting with membrane-associated molecules such as endothelial nitric oxide synthase and tyrosine kinases, precisely regulate cell-signalling pathways responsible for cell structure and cell function. Indeed, there is widespread evidence that caveolae associate, structurally and functionally, with
Joanna M, Biazik +2 more
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Caveats of caveolin-1 in cancer progression
Cancer Letters, 2008Caveolin-1, an essential scaffold protein of caveolae and cellular transport processes, lately gained recognition as a stage- and tissue-specific tumor modulator in vivo. Patient studies and rodent models corroborated its janus-faced role as a tumor suppressor in non-neoplastic tissue, its down-regulation (loss of function) upon transformation and its ...
Elke, Burgermeister +4 more
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Tyrosine Phosphorylation of Caveolin-1 in the Endothelium
Experimental Cell Research, 1999Caveolin-1, a scaffolding protein of caveolae, is known to be tyrosine-phosphorylated by Src kinases. Recently we generated a specific antibody to caveolin-1 phosphorylated at tyrosine-14 (PY14) (R. Nomura and T. Fujimoto, 1999, Mol. Biol. Cell 10, 975-986).
T, Aoki, R, Nomura, T, Fujimoto
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Oxidative Stress, Caveolae and Caveolin-1
2004Oxidative stress underlies a range of pathophysiological conditions. Reactive oxygen species are also generated intracellularly to serve as second messengers and some are linked to caveolae/raft signalling systems. The effect of oxidative stress on caveolin-1 expression, post-translational modifications, membrane trafficking and function are described.
Parat, Marie-Odile, Fox, Paul L
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The role of caveolin‐1 in cardiovascular regulation
Acta Physiologica, 2009AbstractCaveolae are omega‐shaped membrane invaginations present in essentially all cell types in the cardiovascular system, and numerous functions have been ascribed to these structures. Caveolae formation depends on caveolins, cholesterol and polymerase I and transcript release factor‐Cavin (PTRF‐Cavin).
A, Rahman, K, Swärd
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