Results 21 to 30 of about 87,062 (309)

Biomimetic Nanocarrier Targeting Drug(s) to Upstream-Receptor Mechanisms in Dementia: Focusing on Linking Pathogenic Cascades

open access: yesBiomimetics, 2020
Past published studies have already documented that, subsequent to the intravenous injection of colloidal lipid nanocarriers, apolipoprotein (apo)A-I is adsorbed from the blood onto the nanoparticle surface.
Joseph S. D’Arrigo
doaj   +1 more source

Analysis of Bulb Turbine Hydrofoil Cavitation

open access: yesApplied Sciences, 2021
The influence of a bulb runner blade hydrofoil shape on flow characteristics around the blade was studied. Experimental work was performed on a bulb turbine measuring station and a single hydrofoil in a cavitating tunnel.
Andrej Podnar   +3 more
doaj   +1 more source

Scaling of cavitation erosion progression with cavitation intensity and cavitation source [PDF]

open access: yesWear, 2012
Abstract A simple mathematical expression is presented to describe cavitation mean depth of erosion versus time for cavitating jets and ultrasonic cavitation. Following normalization with a characteristic time, t* , which occurs at 75% of the time of maximum rate of erosion, and a corresponding material characteristic mean erosion depth, h* , the ...
Jin-Keun Choi   +2 more
openaire   +1 more source

Alzheimer’s Disease, Brain Injury, and C.N.S. Nanotherapy in Humans: Sonoporation Augmenting Drug Targeting

open access: yesMedical Sciences, 2017
Owing to the complexity of neurodegenerative diseases, multiple cellular types need to be targeted simultaneously in order for a given therapy to demonstrate any major effectiveness.
Joseph S. D’Arrigo
doaj   +1 more source

Analysis of Cavitation Instabilities in a Four-Blade Inducer [PDF]

open access: yes, 2012
The cavitating behavior of a four-blade inducer tested in the LML laboratory large test facility is considered in the present paper. Experimental investigations based on unsteady pressure measurements and records from a six-component balance mounted on ...
DAZIN, Antoine   +7 more
core   +1 more source

Acoustic cavitation rheometry [PDF]

open access: yesSoft Matter, 2021
Acoustic cavitation generated via high-amplitude ultrasound is used to characterize the high strain-rate mechanical properties of agarose hydrogels.
Lauren Mancia   +7 more
openaire   +4 more sources

Cavity induced vibration of flexible hydrofoils [PDF]

open access: yes, 2014
The objective of this work is to investigate the influence of cavity-induced vibrations on the dynamic response and stability of a NACA66 hydrofoil at 8° angle of attack at Re=750 000 via combined experimental measurements and numerical simulations.
CHAE, Eun Jung   +4 more
core   +1 more source

Experiment and numerical simulation investigation on cavitation evolution and damage in the throttling section of pressure reducing valve

open access: yesEnergy Science & Engineering, 2022
For the phenomenon of widespread and serious cavitation damage in the throttling section of pressure reducing valve under high temperature and high pressure in the chemical technology process of petroleum and coal, according to actual coordination ...
Aoqiang Duan   +6 more
doaj   +1 more source

Targeting Early Dementia: Using Lipid Cubic Phase Nanocarriers to Cross the Blood–Brain Barrier

open access: yesBiomimetics, 2018
Over the past decades, a frequent co-morbidity of cerebrovascular pathology and Alzheimer’s disease has been observed. Numerous published studies indicate that the preservation of a healthy cerebrovascular endothelium can be an important therapeutic ...
Joseph S. D’Arrigo
doaj   +1 more source

Nanotargeting of Drug(s) for Delaying Dementia: Relevance of Covid-19 Impact on Dementia

open access: yesAmerican Journal of Alzheimer's Disease and Other Dementias, 2020
By incorporating appropriate drug(s) into lipid (biobased) nanocarriers, one obtains a combination therapeutic for dementia treatment that targets certain cell-surface scavenger receptors (mainly class B type I, or “SR-BI”) and thereby crosses the blood ...
Joseph S. D’Arrigo PhD
doaj   +1 more source

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