Cazymes - Open Access .click

Nature Reviews Microbiology, 2022
The 1013-1014 microorganisms present in the human gut (collectively known as the human gut microbiota) dedicate substantial percentages of their genomes to the degradation and uptake of carbohydrates, indicating the importance of this class of molecules.
Stephen Withers, Jacob Wardman, Peter Rahfeld +2 more
exaly +3 more sources

The continuing expansion of CAZymes and their families

Current Opinion in Chemical Biology, 2019
Carbohydrate-active enzymes (CAZymes) catalyze the assembly and breakdown of glycans and glycoconjugates. Some have been discovered, studied and exploited for numerous applications long ago. For instance, amylase and invertase were isolated in the second half of the 19th century and lysozyme was the first enzyme whose 3-D structure was determined.
Marie-Line Garron, Bernard Henrissat
exaly +5 more sources

Long-Read Metagenomics and CAZyme Discovery

2023
Microorganisms play a primary role in regulating biogeochemical cycles and are a valuable source of enzymes that have biotechnological applications, such as carbohydrate-active enzymes (CAZymes). However, the inability to culture the majority of microorganisms that exist in natural ecosystems restricts access to potentially novel bacteria and ...
Ferrillo, Alessandra +6 more
openaire +3 more sources

CAZyme discovery and design for sweet dreams

Current Opinion in Chemical Biology, 2014
Development of synthetic routes to complex carbohydrates and glyco-conjugates is often hampered by the lack of enzymes with requisite properties or specificities. Indeed, assembly or degradation of carbohydrates requires carbohydrate-active enzymes (CAZymes) able to act on a vast range of glycosidic monomers, oligomers or polymers in a regio-specific ...
André, Isabelle +4 more
openaire +5 more sources

2. zero hunger
humans
carbohydrate metabolism

polysaccharides
metagenomics
carbohydrate-active enzymes

cazyme
metagenome
bacteria