Results 61 to 70 of about 104,865 (293)
Predictors of Survival after Vaccination in a Pneumonic Plague Model
Background: The need for an updated plague vaccine is highlighted by outbreaks in endemic regions together with the pandemic potential of this disease. There is no easily available, approved vaccine. Methods: Here we have used a murine model of pneumonic
Barry D. Moore +10 more
doaj +1 more source
How to take into account general and contextual knowledge for interactive aiding design: Towards the coupling of CSP and CBR approaches [PDF]
The goal of this paper is to show how it is possible to support design decisions with two different tools relying on two kinds of knowledge: case-based reasoning operating with contextual knowledge embodied in past cases and constraint filtering that ...
Aldanondo, Michel +5 more
core +3 more sources
Dimensions and Values for Legal CBR [PDF]
We build on two recent attempts to formalise reasoning with dimensions which effectively map dimensions into factors. These enable propositional reasoning, but sometimes a balance between dimensions needs to be struck, and to permit trade offs we need to keep the magnitudes and so reason more geometrically.
Trevor J. M. Bench-Capon, Katie Atkinson
openaire +1 more source
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
A Novel Marmoset (Callithrix jacchus) Model of Human Inhalational Q Fever
Common marmosets (Callithrix jacchus) were shown to be susceptible to inhalational infection with Coxiella burnetii, in a dose-dependent manner, producing a disease similar to human Q fever, characterized by a resolving febrile response. Illness was also
Michelle Nelson +3 more
doaj +1 more source
An ion‐dipole interaction based strategy is proposed to capture thermodynamically unstable solvents and restructure the coordination environment of calcium ions by introducing ionic liquid co‐solvents, thus suppressing excessive solvent decomposition. Therefore, a smooth and dense solid‐electrolyte interphase dominated by inorganic components is formed
Yunyun Gao +7 more
wiley +1 more source
Assessment of CD200R Activation in Combination with Doxycycline in a Model of Melioidosis
Antimicrobial resistance continues to be a global issue. Pathogens, such as Burkholderia pseudomallei, have evolved mechanisms to efflux certain antibiotics and manipulate the host response.
R. E. Thom +9 more
doaj +1 more source
GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis
This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang +9 more
wiley +1 more source
In supporting the environmental conservation program, protecting the earth from damage caused by human activities and unfriendly activities, it is necessary to instill early education about preserving the environment and conservating the earth free of ...
Chusnul Chotimah
doaj +1 more source
Effect of Soil Stabilization on Subgrade Soil Using Cement, Lime and Fly Ash
Subgrade soil plays an important role in road structural design; therefore, poor subgrade soil may cause insufficient support for the pavement and may reduce its life. The poor properties subgrade soil should be replaced with a strong soil to improve the
Shalaw Abdullah Saleh +2 more
doaj +1 more source

