Results 81 to 90 of about 104,865 (293)

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Repositioned Kirschner Wires as a Temporary Metaphyseal Block to Prevent Articular Extension During Opening‐Wedge High Tibial Osteotomy

Arthroscopy Techniques, EarlyView.
Abstract Lateral hinge fracture is a frequent complication of medial opening‐wedge high tibial osteotomy. Previous strategies—such as inserting an additional third Kirschner wire (K‐wire) from the lateral tibial cortex—reinforce the lateral cortex but do not address the potential fracture line that propagates proximally toward the tibial plateau and ...
Luis García Bordes, Xavier Cuscó Segarra, Pedro Álvarez Díaz, Roberto Seijas Vázquez, David Barastegui Fernández, Paula Velasco Alcalde, Ramón Cugat Bertomeu   +6 more
wiley   +1 more source

Virtual Reality as an environment for CBR [PDF]

, 1998
This paper presents the results of an investigation into the suitability of a Virtual Reality (VR) environment for case-based reasoning (CBR). The paper will show that for problem domains where visualisation of the case is important (e.g. in design or training applications) VR environments have great potential. A prototype has been developed as part of
Ian D. Watson, Leonardo Oliveira
openaire   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Does Sustainability Auditing Lead to Enhanced Corporate Governance, Environmental Performance, and Financial Outcomes? Empirical Evidence From High‐Impact Industries

Business Strategy and the Environment, EarlyView.
ABSTRACT This study employs hierarchical regression modelling on a survey of 550 firms from Nigeria and Ghana to examine the impact of sustainability auditing on corporate governance, environmental performance, and financial outcomes of high‐impact industries.
Mandella Osei‐Assibey Bonsu, Ying Wang, Grace Eghe‐Ikhurhe, Katie Hyslop   +3 more
wiley   +1 more source

Community Approaches to Handicap in Development (CAHD): The Next Generation of CBR Programmes [PDF]

, 2001
This paper has presented the basis of one approach to addressing disability in developing countries. Community Approaches to Handicap in Development (CAHD) builds on the pioneering work done by others in the CBR field and presents a bridge between CBR ...
Krefting, Douglas, Krefting, Laura
core   +1 more source

Sustainability‐Oriented Innovation and Circular Economy Transitions: Evidence From the UK Textile and Clothing Industry

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition to a circular economy (CE) in the textile and clothing (TC) industry is frequently attributed to sustainability‐oriented innovation (SOI), yet empirical understanding of the systemic conditions under which SOI enables CE remains underdeveloped.
Krishnendu Saha, Narain Gupta, Deniz E. Yoruk, Vikas Kumar   +3 more
wiley   +1 more source

Generative AI, ESG Sensemaking, and Environmental Performance: an OIPT Perspective

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite growing enthusiasm for generative artificial intelligence (GenAI) in sustainability management, it remains unclear how such technologies translate vast ESG information into meaningful environmental outcomes. This study addresses this gap by investigating how ESG sensemaking capability mediates the relationship between GenAI integration
Surajit Bag, Gautam Srivastava, Susmi Routray, Andrea Chiarini   +3 more
wiley   +1 more source

Analysis Framework for Opportunistic Spectrum OFDMA and its Application to the IEEE 802.22 Standard

, 2012
We present an analytical model that enables throughput evaluation of Opportunistic Spectrum Orthogonal Frequency Division Multiple Access (OS-OFDMA) networks.
Grønsund, Pål, Park, Jihoon, Pawełczak, Przemysław, Čabrić, Danijela   +3 more
core   +1 more source