Results 71 to 80 of about 103,123 (277)

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Integration of linked open data in case-based reasoning systems [PDF]

open access: yes, 2010
This paper discusses the opportunities of integrating Linked Open Data (LOD) resources into Case-Based Reasoning (CBR) systems. Upon the application domain travel medicine, we will exemplify how LOD can be used to fill three out of four knowledge ...
Althoff, Klaus-Dieter   +2 more
core   +1 more source

Unicast Barrage Relay Networks: Outage Analysis and Optimization

open access: yes, 2015
Barrage relays networks (BRNs) are ad hoc networks built on a rapid cooperative flooding primitive as opposed to the traditional point-to-point link abstraction. Controlled barrage regions (CBRs) can be used to contain this flooding primitive for unicast
Halford, Thomas R.   +2 more
core   +1 more source

Constructing Ontology-Based Cancer Treatment Decision Support System with Case-Based Reasoning [PDF]

open access: yes, 2018
Decision support is a probabilistic and quantitative method designed for modeling problems in situations with ambiguity. Computer technology can be employed to provide clinical decision support and treatment recommendations.
Colloc, Joël   +4 more
core   +2 more sources

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Cold Dark Matter Models [PDF]

open access: yes, 1996
Motivated by inflation, the theory of big-bang nucleosynthesis and the quest for a deeper understanding of the fundamental forces and particles, a very successful paradigm for the development of structure in the Universe has evolved.
Dodelson, Scott   +2 more
core   +2 more sources

The Role of Sustainable Social Media Marketing Activities in Raising Bottom‐of‐the‐Pyramid Customers' Engagement, Satisfaction, and Subjective Well‐Being

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Though prior studies have explored the effects of firms' social media marketing activities on customer engagement, the dynamics characterizing this association in bottom‐of‐the‐pyramid (BoP) markets remain tenuous, exposing a critical gap. Addressing this gap, we develop and test a model assessing (a) the effects of firms' sustainable social ...
Md. Al Amin   +4 more
wiley   +1 more source

Neutrinos And Big Bang Nucleosynthesis

open access: yes, 2005
The early universe provides a unique laboratory for probing the frontiers of particle physics in general and neutrino physics in particular. The primordial abundances of the relic nuclei produced during the first few minutes of the evolution of the ...
Bonifacio P   +8 more
core   +1 more source

The Cosmological Tests [PDF]

open access: yes, 2001
Recent observational advances have considerably improved the cosmological tests, adding to the lines of evidence, and showing that some issues under discussion just a few years ago may now be considered resolved or irrelevant.
Peebles, P. J. E.
core   +2 more sources

Green Human Resource Management and Employee Green Behaviour in Hotels: Mediating Roles of Job Satisfaction and Work Well‐Being

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study investigates the impact of green human resource management (GHRM) practices on employee green behavioural intention (GBI) and in‐role green behaviour (EGB‐IR) in the hospitality sector. Drawing on conservation of resources (COR) theory, we examine the mediating roles of job satisfaction and employee well‐being as psychological ...
Vanessa Guerra‐Lombardi   +3 more
wiley   +1 more source

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