Results 91 to 100 of about 88,115 (330)

TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]

, 2019
OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core   +2 more sources

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Novel biomarkers of inflammation-associated immunity in cervical cancer

Frontiers in Oncology
BackgroundCervical cancer (CC) is a highly malignant gynecological cancer with a direct causal link to inflammation, primarily resulting from persistent high-risk human papillomavirus (HPV) infection.
Weihong Zhao, Qi Li, Qi Li, Songquan Wen, Songquan Wen, Yaqin Li, Ying Bai, Ying Bai, Zhiyu Tian, Zhiyu Tian   +9 more
doaj   +1 more source

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease [PDF]

, 2015
G protein-coupled receptor 35 (GPR35) is an orphan receptor, discovered in 1998, that has garnered interest as a potential therapeutic target through its association with a range of diseases.
Amanda E Mackenzie, Graeme eMilligan, Nina eDivorty, Nina eDivorty, Stuart A. Nicklin   +4 more
core   +3 more sources

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

As quimiocinas e os seus receptores: características e funções fisiológicas.

Acta Médica Portuguesa, 2011
Chemokines are members of a large family of small soluble proteins, which were discovered by their adhesion control, chemotaxis and leukocyte activation abilities.
Rita Guerreiro, Quirina Santos-Costa, J M Azevedo-Pereira   +2 more
doaj   +1 more source

The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases. [PDF]

, 2015
The systemic and organ-specific human fibrotic disorders collectively represent one of the most serious health problems world-wide causing a large proportion of the total world population mortality.
Ballater R, Beon M, Bryan N, Butterfield TA, Connolly MK, Desmoulière A, Fallowfield JA, Galván‐Peña S, Gordon S, Goumans M, Hu B, Ito T, Jimenez SA, Korns D, Krieg T, Lassen S, Lech M, Leibovich SJ, Lev B, Mantovani A, Mantovani A, Molumdar K, Nestle FO, O’Doherty U, Piera‐Velazquez S, Poland GA, Rafii R, Rigamonte E, Tacke F, Venbervliet B, Wang Y, Wick G, Wijesundera KK   +32 more
core   +2 more sources

PRELIVE: A Framework for Predicting Lipid Nanoparticles In Vivo Efficacy and Reducing Reliance on Animal Testing

Advanced Functional Materials, EarlyView.
PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy, Chuan‐En Lu, Kai Liu, Audrey Gallud   +3 more
wiley   +1 more source

A Study of CD4, CCR3, CCR4, CCR5, CXCR3 Expression in Peripheral Blood Lymphocytes of Patients with Gastric Cancer

مجله دانشکده پزشکی اصفهان, 2012
Background: Based on the different expression of chemokine receptors in immune cells, we hypothesized that there would be an alteration in the relative expression of these receptors by T helper cells (Th1 and Th2) during the progression of a malignancy ...
Alireza Andalib, Hassan Dolabi, Abbas Rezaei, Mohamad Reza Maracy, Seyed Javad Hasheminia   +4 more
doaj  

Structure and function of A41, a vaccinia virus chemokine binding protein.

PLoS Pathogens, 2008
The vaccinia virus (VACV) A41L gene encodes a secreted 30 kDa glycoprotein that is nonessential for virus replication but affects the host response to infection.
Mohammad W Bahar, Julia C Kenyon, Mike M Putz, Nicola G A Abrescia, James E Pease, Emma L Wise, David I Stuart, Geoffrey L Smith, Jonathan M Grimes   +8 more
doaj   +1 more source