Nano-Luciferase complementation assay of human herpesvirus 8 chemo/cytokine-receptor interactions. [PDF]
Palande V, Roden RBS, Choi YB.
europepmc +1 more source
Myocardial expression of CC- and CXC-chemokines and their receptors in human end-stage heart failure [PDF]
J Damås
openalex +1 more source
CC Chemokine Receptor 5 (CCR5) Desensitization [PDF]
Jean-Michel Escola +4 more
openaire +1 more source
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui +18 more
wiley +1 more source
CD Molecules Nomenclature 2025: Antibody Validation and Expression Profiling of Immune System G Protein-Coupled Receptors. [PDF]
Fernández-Calles J +9 more
europepmc +1 more source
The upregulation of CC chemokine receptor 7 and the increased migration of maturing dendritic cells to macrophage inflammatory protein 3β and secondary lymphoid chemokine is mediated by the p38 stress‐activated protein kinase pathway [PDF]
Kirit M. Ardeshna +4 more
openalex +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
Human and viral chemokines differentially modulate G protein signaling, β-arrestin recruitment and chemotaxis mediated by the viral G protein-coupled receptor ORF74. [PDF]
Kong Q +6 more
europepmc +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source

