Results 241 to 250 of about 94,878 (326)

Biased and Constitutive Signaling in the CC-chemokine Receptor CCR5 by Manipulating the Interface between Transmembrane Helices 6 and 7*

Journal of Biological Chemistry, 2013
A. Steen, S. Thiele, D. Guo, L. S. Hansen, T. Frimurer, M. Rosenkilde   +5 more
semanticscholar   +1 more source

Cardiovascular Disease Meets Cancer: Exploring the Epidemiology in China and Homotherapy Targeting Intersectional Mechanisms

Advanced Science, EarlyView.
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang, Yujie Shan, Shihong Xu, Jing Wang, Meng Luo, Jiaojiao Zhou, Qishan Chen   +6 more
wiley   +1 more source

Chemotaxis-related molecular markers underlying the immune disorder of psoriasis and ulcerative colitis: Preliminary analysis and verification. [PDF]

Medicine (Baltimore)
Zhang Q, Qin X, Liang D, Li W, Luo S, Lin Y.   +5 more
europepmc   +1 more source

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer. [PDF]

FEBS Open Bio
Joshi V, Swati, Mishra A, Panda A, Sharma V.   +4 more
europepmc   +1 more source

Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion

Advanced Science, EarlyView.
This study proposes that adhesion–clutch can mediate both cell motility and immobilization depending on the force amplitude. Weak adhesion–clutch is well‐suited for cell migration, without forming strong adhesions that impede cell motility. It propels rapid dendritic cell migration controlled by extracellular chemicals, as well as pathologically ...
Kentarou Baba, Ami Fukushi‐Kumagai, Megumi Morisaki, Ryosuke Takeuchi, Zhize Xiao, Yoshikazu Nagashima, Mizuki Sakai, Yasuna Higashiguchi, Hiroko Katsuno‐Kambe, Asako Katsuma, Yoshihiro Ueda, Yuji Kamioka, Daisuke Kawauchi, Tatsuo Kinashi, Yonehiro Kanemura, Naoyuki Inagaki   +15 more
wiley   +1 more source

SELP⁺ TEC:CD8⁺ T cell crosstalk associates with improved radiotherapy efficacy in cervical cancer. [PDF]

Mol Cancer
Huang Q, Yang W, Wang F, Huang R, Wang Q, Li X, Lei T, Yue S, Zou W, An Q, Yue J, Hu Q, Liu C.   +12 more
europepmc   +1 more source

Down-regulation of CC chemokine receptor 3 protein and mRNA in human eosinophils mediated by IL-3

, 2002
Yasmin Dulkys, Christof Kluthe, Thomas Buschermöhle, Ines Barg, Sabine Knöl, Alexander Kapp, Amanda Proudfoot, Jörn Elsner   +7 more
openalex   +1 more source

ORL@Cu‐MOF Boost Cuproptosis and Suppress Fatty Acid Metabolism for Cancer Lymph Node Metastasis Synergistic Therapy

Advanced Science, EarlyView.
The fabrication of ORL@Cu‐MOF and the mechanism of synergistic therapy by cuproptosis, reprogram fatty acid metabolism and anti‐PD‐1. Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates.
Zi‐Zhan Li, Yi Liu, Kan Zhou, Lei‐Ming Cao, Guang‐Rui Wang, Jinmei Wu, Yi‐Fu Yu, Yao Xiao, Bing Liu, Qiuji Wu, Zhiyong Song, Lin‐Lin Bu   +11 more
wiley   +1 more source

CXCR6 recruits Th2 cells and promotes liver fibrosis in schistosomiasis japonica. [PDF]

Hepatol Commun
Zhang Y, Luo M, Li J, Guo C, Jiang J, Zhang Y, Ye Q, Ming Y.   +7 more
europepmc   +1 more source