Results 291 to 300 of about 88,115 (330)

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

open access: yesAdvanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H   +13 more
wiley   +1 more source

Progress in structure-based drug development targeting chemokine receptors. [PDF]

open access: yesFront Pharmacol
Wang J   +5 more
europepmc   +1 more source

Development of chemokine network inhibitors using combinatorial saturation mutagenesis. [PDF]

open access: yesCommun Biol
Kryukova J   +7 more
europepmc   +1 more source

Modeling Human Protein Physical Interactions Involved in HIV Attachment In Silico. [PDF]

open access: yesInt J Mol Sci
Davydenko VS   +4 more
europepmc   +1 more source
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CC chemokine receptor 5 and renal-transplant survival

The Lancet, 2001
About 1% of white populations are homozygous carriers of an allele of the gene for the CC chemokine receptor 5 (CCR5) with a 32 bp deletion (CCR5Delta32), which leads to an inactive receptor. During acute and chronic transplant rejection, ligands for CCR5 are upregulated, and the graft is infiltrated by CCR5-positive mononuclear cells.
M, Fischereder   +13 more
openaire   +2 more sources

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