CC/CXC chemokine risk signature at single-cell resolution: a machine learning model for precision stratification in cervical cancer. [PDF]
Xu B, Shi X, Liu Y, Xu L, Zhou Q.
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IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H +13 more
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Progress in structure-based drug development targeting chemokine receptors. [PDF]
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Chemokines: Orchestration of the Tumor Microenvironment and Control of Hepatocellular Carcinoma Progression. [PDF]
Yang J, Lu H, Li L.
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Molecular mechanisms of neutrophil regulatory network in anti-Candida infection. [PDF]
Xu Y, Cheng R, Li W, Yu W, Chen C.
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Development of chemokine network inhibitors using combinatorial saturation mutagenesis. [PDF]
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Modeling Human Protein Physical Interactions Involved in HIV Attachment In Silico. [PDF]
Davydenko VS +4 more
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Unraveling proteomic signatures and neuroinflammatory networks in a CCI rat model of early sciatica: insights for neuropathic pain mechanisms. [PDF]
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CC chemokine receptor 5 and renal-transplant survival
The Lancet, 2001About 1% of white populations are homozygous carriers of an allele of the gene for the CC chemokine receptor 5 (CCR5) with a 32 bp deletion (CCR5Delta32), which leads to an inactive receptor. During acute and chronic transplant rejection, ligands for CCR5 are upregulated, and the graft is infiltrated by CCR5-positive mononuclear cells.
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