Results 61 to 70 of about 190,576 (311)

Propagação de videira in vitro: produção de plantas matrizes básicas de porta-enxento

Agropecuária Catarinense, 2021
As técnicas de cultura in vitro apresentam um grande potencial para a produção de plantas matrizes e mudas de alta qualidade genética e sanidade comprovada.
Aparecido Lima da Silva, Enio Schuck, Robison Borges, Flávia Maia Moreira, Marcelo Borghezan, Liziane Kadine Antunes de Moraes, Célio Air Mikulski, Carolina Quiumento Velloso   +7 more
doaj  

Homomorphic Encryption with CCA Security [PDF]

, 2008
We address the problem of constructing public-key encryption schemes that meaningfully combine useful computability featureswith non-malleability. In particular, we investigate schemes in which anyone can change an encryption of an unknown message minto an encryption of T(m) (as a feature), for a specific set of allowed functions T, but the scheme is ...
Manoj Prabhakaran 0001, Mike Rosulek
openaire   +2 more sources

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

Advanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo, Nirbhik Acharya, Maxwell B. Watkins, Carlos A. Castañeda, Shahar Sukenik   +4 more
wiley   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

sj-docx-1-cca-10.1177_18681026221100564 - Supplemental material for Selection of China's Top Leadership Cadre: The Roles of Supreme Leaders, Factional Networks, and Candidate Attributes

, 2022
Supplemental material, sj-docx-1-cca-10.1177_18681026221100564 for Selection of China's Top Leadership Cadre: The Roles of Supreme Leaders, Factional Networks, and Candidate Attributes by Jingnan Liu in Journal of Current Chinese ...
Jingnan Liu (2219029)
core   +1 more source

A Brain‐Penetrant Nanobody Reveals GSK3β‐Driven Proline‐Directed Phosphorylation as a Master Regulator of Ischemic Neurodegeneration

Advanced Science, EarlyView.
A brain‐targeted nanoparticle enables delivery of a therapeutic nanobody (Nb.29E9) that inhibits pathogenic GSK3β signaling. This intervention restores AMPK/mTORC1/TGFβ homeostasis, attenuates neuroinflammation and oxidative stress, and promotes long‐term functional recovery after ischemic stroke.
Lan Li, Muyang Li, Lei Sun, Ying Yang, Yuanshun Wu, Ziyi Yin, Anni Wang, Peiyang Zhou, Shaoxiang Luo, Jian Chen, Jun Qin, Zhibing Ai, Zilong Yuan, Zhiqiang Dong, Min Zhang   +14 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

EVALUATION OF PHYSICAL-CHEMICAL CHARACTERISTICS AND ACCEPTANCE OF CROCANTELA LETTUCE PRODUCED IN HYDROPONIC SYSTEM IN ARARAS CITY, SÃO PAULO

Demetra, 2018
The Crocantela lettuce, from the group of crisp lettuce, was developed with similar characteristics to the crisp, ruffled leaf cultivars, with high yield both in field and hydroponic cultivations. In addition to the productive efficiency, it is important
Carolina Medeiros Vicentini-Polette, Fernando César Sala, Marta Helena Fillet Spoto, Marcos David Ferreira, Karla Rodrigues Borba, Marta Regina Verruma-Bernardi   +5 more
doaj   +1 more source

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo, Rong Hu, Yuhang Hu, Ping Hu, Shengbo Han, Guozheng Lv, Zhu Zeng, Yong Zhao, Yang Li, Yan Huang, Yingsong Zhao, Hongda Wang, Guangyu Zhao, Eryang Zhao, Gang Zhao   +14 more
wiley   +1 more source

Atividade forrageira da abelha Apis mellifera sobre as flores da aroeira-vermelha

Agropecuária Catarinense, 2021
O levantamento da abundância e freqüência das abelhas Apis mellifera scutellata, Lepeletier (1836), e as observações do seu comportamento sobre as flores da aroeira-vermelha foram desenvolvidos durante dois ciclos reprodutivos da espécie. Foram coletadas
Maurício Lenzi, Afonso Inácio Orth
doaj