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Monoallelic expression of IGF2 is regulated by CCCTC binding factor (CTCF) binding to the imprinting control region (ICR) on the maternal allele, with subsequent formation of an intrachromosomal loop to the promoter region.
He Zhang, Jifan Hu, Guanxiang Qian
exaly +2 more sources
Promoter-proximal CCCTC-factor binding is associated with an increase in the transcriptional pausing index [PDF]
Motivation: It has been known for more than 2 decades that after RNA polymerase II (RNAPII) initiates transcription, it can enter into a paused or stalled state immediately downstream of the transcription start site before productive elongation.
Sur Herrera Paredes, Praveen Sethupathy
exaly +2 more sources
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Deep Learning of Sequence Patterns for CCCTC-Binding Factor-Mediated Chromatin Loop Formation
Journal of Computational Biology, 2021Liangjiang Wang
exaly
CCCTC-binding factor controls the homeostatic maintenance and migration of Langerhans cells
Journal of Allergy and Clinical Immunology, 2015Min-Geol Lee +2 more
exaly
Cohesin mediates transcriptional insulation by CCCTC-binding factor
Nature, 2008Tsuyoshi Mishiro +2 more
exaly
Proceedings of the National Academy of Sciences of the United States of America, 2010
Jeffrey Milbrandt, Niels Galjart
exaly
Jeffrey Milbrandt, Niels Galjart
exaly

