Results 41 to 50 of about 3,609 (205)

Comparison of diagnostic performances of ten different immunoassays detecting anti-CCHFV IgM and IgG antibodies from acute to subsided phases of Crimean-Congo hemorrhagic fever.

PLoS Neglected Tropical Diseases, 2021
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a geographically widespread tick-borne arbovirus that has been recognized by the WHO as an emerging pathogen needing urgent attention to ensure preparedness for potential outbreaks. Therefore, availability
Petra Emmerich, Ronald von Possel, Christina Deschermeier, Salih Ahmeti, Lindita Berisha, Bahrije Halili, Xhevat Jakupi, Kurtesh Sherifi, Claudia Messing, Viola Borchardt-Lohölter   +9 more
doaj   +1 more source

Unveiling the threat: Balochistan's path to congo virus endemicity

Journal of the Pakistan Medical Association
Dear Madam, The detection of 16 cases of Crimean Congo Haemorrhagic Fever Virus (CCHFV) in the Balochistan province this year (1) and a 2020 study indicating a seroprevalence of 2.7% in humans and 36.2% in livestock in Pakistan, with Balochistan ...
Rida Irfan, Noor Ul Huda, Maryum Imran, Javeria Kamran   +3 more
doaj   +1 more source

Comparative infections of wild-type CCHFV and reporter CCHFV/ZsG.

, 2019
(A) Survival and (B) weight change in Ifnar-/- mice inoculated subcutaneously with 100 TCID50 recombinant wild-type CCHFV (CCHFV; black line with circles; n = 5) or recombinant CCHFV expressing ZsG (CCHFV/ZsG; green line with squares; n = 5).
Gary P. Kobinger (8067335), Stuart T. Nichol (8067341), Anita K. McElroy (8067326), Jessica R. Harmon (5540843), Jessica R. Spengler (8067344), JoAnn D. Coleman-McCray (8067329), Jana M. Ritter (8067323), Sherif R. Zaki (8067338), Éric Bergeron (5663428), Florine E. M. Scholte (8067332), Stephen R. Welch (8067320), Christina F. Spiropoulou (8067347)   +11 more
core   +1 more source

Furin enhances CCHFV propagation.

, 2015
CHO-derived cell lines used were parental clone 6 (Par6), furin-deficient (FD11), and FD11 stably expressing furin (FD11-Fur). Each cell line was infected with CCHFV at multiplicity of infection (MOI) = 1 or with Rift Valley fever virus expressing EGFP ...
Marko Zivcec (191739), Christina F. Spiropoulou (139312), César G. Albariño (139297), Ayan K. Chakrabarti (139299), Stuart T. Nichol (130422), Éric Bergeron (5663428)   +5 more
core   +1 more source

Crimean‐Congo Haemorrhagic Fever Virus Exposure in Horses and Donkeys in Border Livestock Markets of Nigeria

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Crimean‐Congo haemorrhagic fever virus (CCHFV) is a tick‐borne zoonotic pathogen of major public health importance in Africa. Although CCHFV exposure has been reported in several livestock species in Nigeria, data on equids remain limited despite their extensive involvement in livestock movement and trade.
David O. Ehizibolo, Olumuyiwa Oyekan, Nicodemus Mkpuma, Habibu Haliru, Ibrahim Garba, Isa Z. Turaki, Samdi Kennedy, Joshua M. Shallangwa, Caleb S. Kilyobas, Abdullahi Mohammed, Musa A. Muhammad, Mansur Abubakar, Maryam Muhammad, Corrie Brown, Bonto Faburay   +14 more
wiley   +1 more source

Immune responses in multiple hosts to Nucleocapsid Protein (NP) of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)

PLOS Neglected Tropical Diseases, 2021
In 2019, the World Health Organization declared 3 billion to be at risk of developing Crimean Congo Hemorrhagic Fever (CCHF). The causative agent of this deadly infection is CCHFV. The data related to the biology and immunology of CCHFV are rather scarce.
Elif Karaaslan, Nesibe Selma Çetin, Merve Kalkan-Yazıcı, Sevde Hasanoğlu, Faruk Karakeçili, Aykut Özdarendeli, Ahmet Kalkan, Ali Osman Kılıç, Mehmet Ziya Doymaz   +8 more
openaire   +7 more sources

CCHFV induces TRAIL alternative splicing.

, 2013
CCHFV-infected cells were examined for the (A) the expression levels of TRAIL by conventional RT-PCR (H is the heteroduplex, U the unspliced and S the spliced form of the TRAIL transcript) or (B) the expression levels of TRAIL-R2 by real time qRT-PCR ...
Guy Vernet (174407), Gláucia Paranhos-Baccalà (174398), Raquel Rodrigues (221129), Christophe N. Peyrefitte (335829)   +3 more
core   +1 more source

Multiple Reassortments, Limited Geographic Spread, and Comparable Pathogenicity of Crimean‐Congo Hemorrhagic Fever Viruses in Sivas Province, Türkiye

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Crimean‐Congo hemorrhagic fever virus (CCHFV) is a segmented RNA virus that can cause severe hemorrhagic fever and is primarily transmitted to humans and other mammals through tick bites. Since segment reassortment can increase genetic diversity and disease severity, we sampled infected ticks and humans in Sivas Province, Türkiye, a region ...
Qianying Lin, Nazif Elaldi, Mesut Yigit, Baris Yildiz, Roger Hewson, Martín López‐García, Grant Lythe, Ayse Nur Pektas, Binnur Koksal, Tuba Nur Tasseten, Ahmet Deniz, Hilal Bedir, Yasemin Cakir Kiymaz, Zati Vatansever, Carmen Molina‐París, Thomas Leitner   +15 more
wiley   +1 more source

Identifying main drivers and testing control strategies for CCHFV spread

Experimental and Applied Acarology, 2015
Crimean Congo Haemorrhagic Fever (CCHF) is an emerging zoonotic disease. The causative agent is a virus (CCHFV), mainly transmitted by ticks of the species Hyalomma marginatum in Eastern Europe and Turkey. In order to test potential scenarios for the control of pathogen spread, the basic reproduction number (R0) for CCHF was calculated.
Hoch, Thierry, Breton, Eric, Josse, Mathilde, Deniz, Ahmet, Guven, Esin, Vatansever, Zati   +5 more
openaire   +6 more sources

Prokaryotic expression and purification of CCHFV-NP.

, 2018
(A) Primary structure of recombinant CCHFV-NP fusion protein encoded by the expression vector pOPINJ-CCHFV-NP (6xHis-GST-3C-CCHFV-NP). The full-length CCHFV-NP is N-terminally tagged with both a 6 x His-tag and GST. A 3C protease recognition site enables
Christina Deschermeier (207807), Ronald von Possel (5007197), Kurtesh Sherifi (634266), Xhevat Jakupi (508103), Herbert Schmitz (502023), Yang Liu (4829), Barie Halili (5007206), Lindita Berisha (5007200), Anne Rackow (5007203), Stephan Günther (218223), Petra Emmerich (331026), Salih Ahmeti (508104), Angela Mika (152045)   +12 more
core   +1 more source