Results 21 to 30 of about 5,642 (225)

Immune responses in multiple hosts to Nucleocapsid Protein (NP) of Crimean-Congo Hemorrhagic Fever Virus (CCHFV)

PLOS Neglected Tropical Diseases, 2021
In 2019, the World Health Organization declared 3 billion to be at risk of developing Crimean Congo Hemorrhagic Fever (CCHF). The causative agent of this deadly infection is CCHFV. The data related to the biology and immunology of CCHFV are rather scarce.
E. Karaaslan, N. Çetin, Merve Kalkan-Yazıcı, Sevde Hasanoğlu, F. Karakeçili, A. Özdarendeli, A. Kalkan, A. Kiliç, M. Doymaz   +8 more
semanticscholar   +8 more sources

First Whole Genome Sequencing of Crimean–Congo Hemorrhagic Fever Virus (CCHFV) in Tick Species within Ghana

Transboundary and Emerging Diseases, 2023
Crimean–Congo hemorrhagic fever (CCHF) is a serious viral zoonotic disease spread by ticks and caused by the Crimean–Congo hemorrhagic fever virus (CCHFV).
R. Bentil, S. O. Addo, Mba-tihssommah Mosore, Selassie Kumordjie, C. Yeboah, Bright Agbodzi, E. Behene, Janice Tagoe, Bernice Olivia Ama Baako, V. Asoala, Richard Osei Ampadu, D. Mingle, E. Nyarko, A. Fox, A. Letizia, J. Diclaro, Terrel Sanders, Daniel Oduro, Shirley C Nimo-Paintsil, James F Harwood, S. Dadzie   +20 more
semanticscholar   +3 more sources

Comparison of diagnostic performances of ten different immunoassays detecting anti-CCHFV IgM and IgG antibodies from acute to subsided phases of Crimean-Congo hemorrhagic fever.

PLoS Neglected Tropical Diseases, 2021
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a geographically widespread tick-borne arbovirus that has been recognized by the WHO as an emerging pathogen needing urgent attention to ensure preparedness for potential outbreaks. Therefore, availability
Petra Emmerich, Ronald von Possel, Christina Deschermeier, Salih Ahmeti, Lindita Berisha, Bahrije Halili, Xhevat Jakupi, Kurtesh Sherifi, Claudia Messing, Viola Borchardt-Lohölter   +9 more
doaj   +2 more sources

In Silico Analysis of Potential Vaccine Antigens for the Treatment of Crimean-Congo Hemorrhagic Fever Virus (Cchfv). [PDF]

Pharm Res
Background Crimean-Congo hemorrhagic fever virus (CCHFV), identified by the World Health Organization(WHO) as a potential epidemic threat, is a tick-borne Nairovirus primarily transmitted by Hyalomma marginatum species.
Tülümen D, Aydemir E, Ayaz F.
europepmc   +2 more sources

Development of targeted whole genome sequencing approaches for Crimean-Congo haemorrhagic fever virus (CCHFV)

Virus Research
Highlights • A novel probe capture hybridisation method has been developed for CCHFV.• The presented methodology was validated against clinical as well as cell-cultured reference viruses.• The newly developed methodology produced near complete genome ...
Jake D’Addiego, Sonal Shah, Ayşe Nur Pektaş, Binnur Bağcı, Murtaza Öz, Sasha Sebastianelli, N. Elaldı, D. Allen, Roger Hewson   +8 more
semanticscholar   +4 more sources

HuR (ELAVL1) regulates the CCHFV minigenome and HAZV replication by associating with viral genomic RNA

PLOS Neglected Tropical Diseases
Crimean-Congo Hemorrhagic Fever virus (CCHFV) is a tick-borne pathogen that causes severe acute fever disease in humans and requires a biosafety level 4 laboratory for handling.
Moe Ikegawa, Norisuke Kano, D. Ori, Mizuki Fukuta, Minato Hirano, Roger Hewson, Kentaro Yoshii, Taro Kawai, Takumi Kawasaki   +8 more
semanticscholar   +4 more sources

The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity

PLoS Pathogens, 2020
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne orthonairovirus that has become a serious threat to the public health. CCHFV has a single-stranded, tripartite RNA genome composed of L, M, and S segments.
Natalia Freitas, Solene Denolly, Gregory Neveu   +2 more
exaly   +2 more sources

Development of multivalent vaccine targeting M segment of Crimean Congo Hemorrhagic Fever Virus (CCHFV) using immunoinformatic approaches

Saudi Journal of Biological Sciences, 2021
Graphical ...
Maaza Sana, A. Javed, Syed Babar Jamal, M. Junaid, Muhammad Faheem   +4 more
semanticscholar   +3 more sources

Seroepidemiology of Crimean-Congo Hemorrhagic Fever Virus (CCHFV) in Cattle across Three Livestock Pastoral Regions in Kenya [PDF]

Dairy, 2021
Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic disease, endemic in Africa, with a high case fatality rate. There is no efficient treatment or licensed vaccine.
Isabel Blanco-Penedo, V. Obanda, Edward Kingori, B. Agwanda, C. Ahlm, O. Lwande   +5 more
semanticscholar   +5 more sources

Purification of Crimean Congo Hemorrhagic Fever Virus (CCHFV) Nucleocapsid Protein Using Detergent Gradient and Free Thawing.

BIO-PROTOCOL, 2022
Protein aggregation remains a major challenge in the purification of recombinant proteins in both eukaryotic and prokaryotic expression systems. One such protein is the nucleocapsid protein of Crimean Congo Hemorrhagic fever virus (CCHFV), which has high
Austin Royster, S. Mir
semanticscholar   +4 more sources