Results 11 to 20 of about 2,525 (164)

CCHFV Seroprevalence among Hunter-Gatherers, Northeastern Democratic Republic of the Congo [PDF]

Emerging Infectious Diseases
We evaluated human Crimean-Congo hemorrhagic fever virus (CCHFV) seroprevalence in hunter-gatherer populations of northeastern Democratic Republic of the Congo. We tested blood from 300 participants for CCHFV antibodies; 4% were CCHFV-positive.
Dacquin M. Kasumba, Samuel M. Shamamba, Ange Y. Mubiala, Bobo N. Bazola, Amanda C. Horton, Charles Ndawula, Jean-Jacques Muyembe-Tamfum, Jean-Christophe Sabue Mulangu   +7 more
doaj   +3 more sources

Multiple Reassortments, Limited Geographic Spread, and Comparable Pathogenicity of Crimean‐Congo Hemorrhagic Fever Viruses in Sivas Province, Türkiye [PDF]

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Crimean‐Congo hemorrhagic fever virus (CCHFV) is a segmented RNA virus that can cause severe hemorrhagic fever and is primarily transmitted to humans and other mammals through tick bites. Since segment reassortment can increase genetic diversity and disease severity, we sampled infected ticks and humans in Sivas Province, Türkiye, a region ...
Qianying Lin, Nazif Elaldi, Mesut Yigit, Baris Yildiz, Roger Hewson, Martín López‐García, Grant Lythe, Ayse Nur Pektas, Binnur Koksal, Tuba Nur Tasseten, Ahmet Deniz, Hilal Bedir, Yasemin Cakir Kiymaz, Zati Vatansever, Carmen Molina‐París, Thomas Leitner   +15 more
wiley   +2 more sources

Host Community Traits Driving Crimean‐Congo Hemorrhagic Fever Virus Maintenance in Iberian Ecosystems [PDF]

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Crimean‐Congo hemorrhagic fever (CCHF) is a tick‐borne zoonosis of significant public health concern, maintained in complex multihost systems shaped by ecological, climatic, and anthropogenic drivers. In the Iberian Peninsula, changing land‐use patterns and biodiversity loss may be reshaping host communities in ways that alter local transmission ...
Patrícia Xavier, Alberto Perelló, Víctor Luque-Castro, David Relimpio, Patricia Barroso, Virgílio Almeida, José de la Fuente, Ana Balseiro, Francisco Ruiz-Fons, Christian Gortázar, Laurent Dacheux   +10 more
wiley   +2 more sources

Widespread circulation of Crimean-Congo haemorrhagic fever virus in ticks, Corsica (France), 2024 [PDF]

One Health
Crimean-Congo Haemorrhagic Fever is a severe tick-borne viral disease with a high fatality rate. This study aimed to advance the understanding of CCHF virus (CCHFV) in terms of geographical spread and genotypic characterization by investigating its ...
Morena Gasparine, Armand Namekong Fokeng, Shirley Masse, Eva Lopez, Remi Charrel, Xavier de Lamballerie, Alessandra Falchi   +6 more
doaj   +2 more sources

The Crimean-Congo haemorrhagic fever virus hijacks the liver lipid metabolic pathway for virion production [PDF]

Emerging Microbes and Infections
The Crimean-Congo Haemorrhagic Fever Virus (CCHFV), a tri-segmented negative-strand virus that belongs to the Orthonairovirus genus, is highly pathogenic in humans but not in other host species.
Anupriya Gautam, Li Zhong, Eva Ogire, Sergueï Bodoirat, Ilary Riedmiller, Willem J. Sander, Bertrand Boson, Apoorv Gandhi, Julien Burlaud-Gaillard, Fouzia Amirache, Vincent Legros, Philippe Roingeard, Vincent Lotteau, Cyrille Mathieu, François-Loïc Cosset, Solène Denolly   +15 more
doaj   +2 more sources

Field vaccination against CCHFV and Hyalomma tick infestation reduces multiple tick-borne infections in sheep [PDF]

npj Vaccines
Abstract Tick-borne pathogens (TBPs) are expanding globally, with their impact on public health expected to rise due to climate change. Immunizing livestock offers a cost-effective alternative or adjunct to human vaccination. We evaluated two DNA vaccines, one targeting Crimean-Congo hemorrhagic fever virus (CCHFV)
Mhamadi, Moufid, Babuadze, George Giorgi, Badji, Aminata, Echanove, Jose, Gaye, Alioune, Ndiaye, El Hadji, Ndiaye, Oumar, Ndiaye, Mignane, Dieng, Idrissa, XIII, Ara, Mhamadi, Moundhir, Touré, Cheikh Talibouya, Fall, Mathioro, Faye, Ousmane, Fausther-Bovendo, Hugues, Faye, Oumar, Sall, Amadou Alpha, Kobinger, Gary   +17 more
openaire   +3 more sources

Convalescent human plasma candidate reference materials protect against Crimean-Congo haemorrhagic fever virus (CCHFV) challenge in an A129 mouse model

Virus Research
Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is spread by infected ticks or direct contact with blood, tissues and fluids from infected patients or livestock.
Sarah Kempster, FRANCISCO J Salguero, Nazif Elaldi   +2 more
exaly   +3 more sources

Genetic features of Orthonairovirus haemorrhagiae variants detected in ixodid ticks in Armenia. [PDF]

PLoS Neglected Tropical Diseases
IntroductionCrimean-Congo hemorrhagic fever (CCHF) is a viral transmissible febrile disease, featuring hemorrhagic manifestations and a high mortality rate, caused by Orthonairovirus haemorrhagiae (CCHFV).
Anna Volynkina, Yana Lisitskaya, Anna Zhirova, Olga Gnusareva, Ekaterina Vasilenko, Lyudmila Shaposhnikova, Sergey Pisarenko, Arsen Manucharyan, Gayane Melik-Andreasyan, Vladimir Dedkov, Anna Dolgova, Alexander Kulichenko   +11 more
doaj   +2 more sources

Development of targeted whole genome sequencing approaches for Crimean-Congo haemorrhagic fever virus (CCHFV)

Virus Research
Crimean-Congo haemorrhagic fever (CCHF) is the most prevalent human tick-borne viral disease, with a reported case fatality rate of 30 % or higher. The virus contains a tri-segmented, negative-sense RNA genome consisting of the small (S), medium (M) and large (L) segments encoding respectively the nucleoprotein (NP), the glycoproteins precursor (GPC ...
Ayse Nur Pektas, David Allen, Roger Hewson   +2 more
exaly   +6 more sources

In Silico Analysis of Potential Vaccine Antigens for the Treatment of Crimean-Congo Hemorrhagic Fever Virus (Cchfv) [PDF]

Pharmaceutical Research
Abstract Background Crimean-Congo hemorrhagic fever virus (CCHFV), identified by the World Health Organization(WHO) as a potential epidemic threat, is a tick-borne Nairovirus primarily transmitted by Hyalomma marginatum species.
Deniz Tülümen, Esra Aydemir, Furkan Ayaz   +2 more
openaire   +3 more sources