Results 11 to 20 of about 3,945 (173)

The low-density lipoprotein receptor and apolipoprotein E associated with CCHFV particles mediate CCHFV entry into cells [PDF]

Nature Communications
The Crimean-Congo hemorrhagic fever virus (CCHFV) is an emerging pathogen of the Orthonairovirus genus that can cause severe and often lethal hemorrhagic diseases in humans. CCHFV has a broad tropism and can infect a variety of species and tissues. Here,
Maureen Ritter, Lola Canus, Anupriya Gautam, Thomas Vallet, Li Zhong, Alexandre Lalande, Bertrand Boson, Apoorv Gandhi, Sergueï Bodoirat, Julien Burlaud-Gaillard, Natalia Freitas, Philippe Roingeard, John N. Barr, Vincent Lotteau, Vincent Legros, Cyrille Mathieu, François-Loïc Cosset, Solène Denolly   +17 more
doaj   +2 more sources

Multiple Reassortments, Limited Geographic Spread, and Comparable Pathogenicity of Crimean-Congo Hemorrhagic Fever Viruses in Sivas Province, Türkiye. [PDF]

J Med Virol
ABSTRACT Crimean‐Congo hemorrhagic fever virus (CCHFV) is a segmented RNA virus that can cause severe hemorrhagic fever and is primarily transmitted to humans and other mammals through tick bites. Since segment reassortment can increase genetic diversity and disease severity, we sampled infected ticks and humans in Sivas Province, Türkiye, a region ...
Lin Q, Elaldi N, Yigit M, Yildiz B, Hewson R, López-García M, Lythe G, Pektas AN, Koksal B, Tasseten TN, Deniz A, Bedir H, Kiymaz YC, Vatansever Z, Molina-París C, Leitner T.   +15 more
europepmc   +2 more sources

Crimean-Congo Haemorrhagic Fever Virus Exposure in Horses and Donkeys in Border Livestock Markets of Nigeria. [PDF]

Zoonoses Public Health
ABSTRACT Introduction Crimean‐Congo haemorrhagic fever virus (CCHFV) is a tick‐borne zoonotic pathogen of major public health importance in Africa. Although CCHFV exposure has been reported in several livestock species in Nigeria, data on equids remain limited despite their extensive involvement in livestock movement and trade.
Ehizibolo DO, Oyekan O, Mkpuma N, Haliru H, Garba I, Turaki IZ, Kennedy S, Shallangwa JM, Kilyobas CS, Mohammed A, Muhammad MA, Abubakar M, Muhammad M, Brown C, Faburay B.   +14 more
europepmc   +2 more sources

NUCLEOSIDE-MODIFIED MRNA VACCINES PROTECT IFNAR -/- MICE AGAINST CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS INFECTION

International Journal of Infectious Diseases, 2023
Intro: Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV), is the causative agent of Crimean-Congo hemorrhagic fever (CCHF). Occurrence of the virus coincides with the distribution of its primary vector and reservoir, Hyalomma ticks.
A. Mirazimi
doaj   +1 more source

GP38 as a vaccine target for Crimean-Congo hemorrhagic fever virus

npj Vaccines, 2023
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic disease in humans. There is a great need for effective vaccines and therapeutics against CCHFV for humans, as none are currently internationally approved ...
Gabrielle Scher, Dennis A. Bente, Megan C. Mears, Maria N. B. Cajimat, Matthias J. Schnell   +4 more
doaj   +1 more source

Construction and evaluation of DNA vaccine encoding Crimean Congo hemorrhagic fever virus nucleocapsid protein, glycoprotein N-terminal and C-terminal fused with LAMP1

Frontiers in Cellular and Infection Microbiology, 2023
Crimean-Congo hemorrhagic fever virus (CCHFV) can cause severe hemorrhagic fever in humans and is mainly transmitted by ticks. There is no effective vaccine for Crimean-Congo hemorrhagic fever (CCHF) at present.
Yong-Liang Hu, Yong-Liang Hu, Lian-Qing Zhang, Lian-Qing Zhang, Xiao-Qian Liu, Xiao-Qian Liu, Wei Ye, Yue-Xi Zhao, Yue-Xi Zhao, Liang Zhang, Zun-Xian Qiang, Lin-Xuan Zhang, Ying-Feng Lei, Dong-Bo Jiang, Lin-Feng Cheng, Fang-Lin Zhang   +15 more
doaj   +1 more source

Purification of Crimean–Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis

Scientific Reports, 2021
Crimean–Congo hemorrhagic fever virus (CCHFV) causes a zoonotic disease, Crimean–Congo hemorrhagic fever (CCHF) endemic in Africa, Asia, the Middle East, and Southeastern Europe.
Boniface Pongombo Lombe, Hiroko Miyamoto, Takeshi Saito, Reiko Yoshida, Rashid Manzoor, Masahiro Kajihara, Masayuki Shimojima, Shuetsu Fukushi, Shigeru Morikawa, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Saijo, Qing Tang, Justin Masumu, David Hawman, Heinz Feldmann, Ayato Takada   +16 more
doaj   +1 more source

CCHFV-related viruses (Family Bunyaviridae).

, 2022
CCHFV-related viruses (Family Bunyaviridae).
Greg Smith (343139), Dominic M. S. Kielich (12225878), James E. Strong (9853839), Hongzhao Li (172496), Alexander Bello (387420), Bradley S. Pickering (8895167)   +5 more
core   +1 more source

Crimean–Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022

Tropical Medicine and Infectious Disease, 2022
Crimean–Congo hemorrhagic fever virus (CCHFV) is widespread in Asia, Europe, and Africa. In Senegal, sporadic cases of CCHFV have been reported since 1960.
Moufid Mhamadi, Aminata Badji, Idrissa Dieng, Alioune Gaye, El Hadji Ndiaye, Mignane Ndiaye, Moundhir Mhamadi, Cheikh Talibouya Touré, Mouhamed Rassoul Mbaye, Mamadou Aliou Barry, Oumar Ndiaye, Babacar Faye, Fatimata Amadou Ba, Boly Diop, Mamadou Ndiaye, Mathioro Fall, Samba Niang Sagne, Gamou Fall, Cheikh Loucoubar, Hugues Fausther-Bovendo, Amadou Alpha Sall, Gary Kobinger, Ousmane Faye, Mawlouth Diallo, Oumar Faye   +24 more
doaj   +1 more source

CCHF Viral RNA, anti-CCHFV IgM and anti-CCHFV IgG kinetics of CCHFV cases.

, 2021
(A) CCHF viral RNA amongst fatal and survivors (B) CCHF viral RNA amongst individual survivors at different time points (C) Anti-CCHFV-IgM antibodies amongst individual survivors at different time points and fatal cases (D) Anti-CCHFV-IgG antibodies ...
Himanshu Kaushal (558851), Rajlaxmi Jain (332241), Alpesh Vora (11356210), Pragya D. Yadav (10122205), Raman R. Gangakhedkar (4319134), Triparna Majumdar (11356201), Rima R. Sahay (10122217), Anita M. Shete (11356198), Chetan L. Varevadiya (11356207), Kamlesh J. Upadhyay (9284145), Dimpal A. Nyayanit (10122220), Savita Patil (10122214), Sunil J. Panjwani (11356204), Amit Kanani (7303268)   +13 more
core   +1 more source