Results 11 to 20 of about 3,609 (205)

The Crimean-Congo haemorrhagic fever virus hijacks the liver lipid metabolic pathway for virion production [PDF]

Emerging Microbes and Infections
The Crimean-Congo Haemorrhagic Fever Virus (CCHFV), a tri-segmented negative-strand virus that belongs to the Orthonairovirus genus, is highly pathogenic in humans but not in other host species.
Anupriya Gautam, Li Zhong, Eva Ogire, Sergueï Bodoirat, Ilary Riedmiller, Willem J. Sander, Bertrand Boson, Apoorv Gandhi, Julien Burlaud-Gaillard, Fouzia Amirache, Vincent Legros, Philippe Roingeard, Vincent Lotteau, Cyrille Mathieu, François-Loïc Cosset, Solène Denolly   +15 more
doaj   +2 more sources

Genetic features of Orthonairovirus haemorrhagiae variants detected in ixodid ticks in Armenia. [PDF]

PLoS Neglected Tropical Diseases
IntroductionCrimean-Congo hemorrhagic fever (CCHF) is a viral transmissible febrile disease, featuring hemorrhagic manifestations and a high mortality rate, caused by Orthonairovirus haemorrhagiae (CCHFV).
Anna Volynkina, Yana Lisitskaya, Anna Zhirova, Olga Gnusareva, Ekaterina Vasilenko, Lyudmila Shaposhnikova, Sergey Pisarenko, Arsen Manucharyan, Gayane Melik-Andreasyan, Vladimir Dedkov, Anna Dolgova, Alexander Kulichenko   +11 more
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HuR (ELAVL1) regulates the CCHFV minigenome and HAZV replication by associating with viral genomic RNA

PLOS Neglected Tropical Diseases
Crimean-Congo Hemorrhagic Fever virus (CCHFV) is a tick-borne pathogen that causes severe acute fever disease in humans and requires a biosafety level 4 laboratory for handling. Hazara virus (HAZV), belonging to the same virus genus as CCHFV, does not exhibit pathogenesis in humans.
Moe Ikegawa, Norisuke Kano, Daisuke Ori, Mizuki Fukuta, Minato Hirano, Roger Hewson, Kentaro Yoshii, Taro Kawai, Takumi Kawasaki   +8 more
openaire   +3 more sources

Convalescent human plasma candidate reference materials protect against Crimean-Congo haemorrhagic fever virus (CCHFV) challenge in an A129 mouse model

Virus Research
Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is spread by infected ticks or direct contact with blood, tissues and fluids from infected patients or livestock.
Sarah L Kempster, Victoria Graham, Stephen Findlay-Wilson   +2 more
exaly   +3 more sources

Crimean-Congo Hemorrhagic Fever Virus (CCHFV): A Silent but Widespread Threat [PDF]

Current Tropical Medicine Reports, 2021
Abstract Purpose of Review This review is aimed at highlighting recent research and articles on the complicated relationship between virus, vector, and host and how biosurveillance at each level informs disease spread and risk.
Paul A. Kuehnert, Christopher P. Stefan, Catherine V. Badger, Keersten M. Ricks   +3 more
openaire   +2 more sources

Development of anti-Crimean-Congo hemorrhagic fever virus Gc and NP-specific ELISA for detection of antibodies in domestic animal sera

Frontiers in Veterinary Science, 2022
Crimean-Congo hemorrhagic fever (CCHF) is a priority emerging disease. CCHF, caused by the CCHF virus (CCHFV), can lead to hemorrhagic fever in humans with severe cases often having fatal outcomes. CCHFV is maintained within a tick-vertebrate-tick cycle,
Sandra Belij-Rammerstorfer, Georgina Limon, Emmanuel A. Maze, Kayleigh Hannant, Ellen Hughes, Simona R. Tchakarova, Tsviatko Alexandrov, Blandina T. Mmbaga, Blandina T. Mmbaga, Brian Willett, George Booth, Nicholas A. Lyons, Natalie Baker, Kelly M. Thomas, Daniel Wright, Jack Saunders, Clare Browning, Ginette Wilsden, Miles Carroll, Roger Hewson, Roger Hewson, Bryan Charleston, Teresa Lambe, Anna B. Ludi   +23 more
doaj   +1 more source

Differential Cell Line Susceptibility to Crimean-Congo Hemorrhagic Fever Virus

Frontiers in Cellular and Infection Microbiology, 2021
Crimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne viral disease of global concerns due to the increasing incidence and lack of effective treatments.
Shiyu Dai, Qiaoli Wu, Xiaoli Wu, Cheng Peng, Jia Liu, Shuang Tang, Tao Zhang, Fei Deng, Shu Shen   +8 more
doaj   +1 more source

GP38 as a vaccine target for Crimean-Congo hemorrhagic fever virus

npj Vaccines, 2023
Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic disease in humans. There is a great need for effective vaccines and therapeutics against CCHFV for humans, as none are currently internationally approved ...
Gabrielle Scher, Dennis A. Bente, Megan C. Mears, Maria N. B. Cajimat, Matthias J. Schnell   +4 more
doaj   +1 more source

Purification of Crimean–Congo hemorrhagic fever virus nucleoprotein and its utility for serological diagnosis

Scientific Reports, 2021
Crimean–Congo hemorrhagic fever virus (CCHFV) causes a zoonotic disease, Crimean–Congo hemorrhagic fever (CCHF) endemic in Africa, Asia, the Middle East, and Southeastern Europe.
Boniface Pongombo Lombe, Hiroko Miyamoto, Takeshi Saito, Reiko Yoshida, Rashid Manzoor, Masahiro Kajihara, Masayuki Shimojima, Shuetsu Fukushi, Shigeru Morikawa, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Saijo, Qing Tang, Justin Masumu, David Hawman, Heinz Feldmann, Ayato Takada   +16 more
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Crimean–Congo Hemorrhagic Fever Virus Survey in Humans, Ticks, and Livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022

Tropical Medicine and Infectious Disease, 2022
Crimean–Congo hemorrhagic fever virus (CCHFV) is widespread in Asia, Europe, and Africa. In Senegal, sporadic cases of CCHFV have been reported since 1960.
Moufid Mhamadi, Aminata Badji, Idrissa Dieng, Alioune Gaye, El Hadji Ndiaye, Mignane Ndiaye, Moundhir Mhamadi, Cheikh Talibouya Touré, Mouhamed Rassoul Mbaye, Mamadou Aliou Barry, Oumar Ndiaye, Babacar Faye, Fatimata Amadou Ba, Boly Diop, Mamadou Ndiaye, Mathioro Fall, Samba Niang Sagne, Gamou Fall, Cheikh Loucoubar, Hugues Fausther-Bovendo, Amadou Alpha Sall, Gary Kobinger, Ousmane Faye, Mawlouth Diallo, Oumar Faye   +24 more
doaj   +1 more source