Results 301 to 310 of about 138,616 (334)

SPACA6-hosted miR-99b~125a~let-7e cluster shapes melanoma resistance by modulating mTOR-mediated immunosuppression. [PDF]

open access: yesFront Immunol
Vallacchi V   +18 more
europepmc   +1 more source
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CCL2 in the Tumor Microenvironment

2021
The C-C motif chemokine ligand 2 (CCL2) is a crucial mediator of immune cell recruitment during microbial infections and tissue damage. CCL2 is also frequently overexpressed in cancer cells and other cells in the tumor microenvironment, and a large body of evidence indicates that high CCL2 levels are associated with more aggressive malignancies, a ...
O'Connor, T., Heikenwälder, M.
openaire   +3 more sources

Nitration of CCL2 disrupts the tumor-protective function of CCL2 in bladder cancer

The Journal of Immunology, 2022
Abstract The chemokine CCL2 (C-C motif ligand 2) is best known for its ability to induce trafficking of immune cells by binding its primary receptor, CCR2. The recruitment of immunosuppressive monocytes by CCL2 promotes cancer in several tumor types. Surprisingly, we previously found an unanticipated protective role for CCL2 signaling in
Neelam Mukherjee   +4 more
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ChemInform Abstract: Fluorination with Concomitant Cyclization of CCl2=N‐CCl2‐CCl2‐N=CCl2 with SbF5 and Molecular Structure of a 2‐Imidazolidinone Derivative.

ChemInform, 1987
AbstractFluorination of the perchlorodiazahexadiene (I) yields the imidazolines (III) or (IV), depending on the amount of the fluorinating agent SbF5 (II) used.
G. PAWELKE   +3 more
openaire   +1 more source

Ccl2 Determinations

Journal AWWA, 2008
On July 30, 2008, the U.S. Environmental Protection Agency (USEPA) finalized the regulatory determinations for 11 contaminants on the Second Contaminant Candidate List (CCL2). Considering the best available data, USEPA concluded that these contaminants occur infrequently at levels of public health concern in public water systems.
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