Results 311 to 320 of about 138,616 (334)

Hyperocclusion Stimulates Osteoclastogenesis via CCL2 Expression

Journal of Dental Research, 2011
Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We hypothesized that MS induces expression of osteoclastogenesis-associated chemokines in PDL tissue, resulting in ...
K T, Goto, H, Kajiya, T, Nemoto, T, Tsutsumi, T, Tsuzuki, H, Sato, K, Okabe   +6 more
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CCL2 (monocyte chemoattractant protein-1) and cancer

Seminars in Cancer Biology, 2004
Genetic analyses of cancer in humans indicate that chemokines and their receptors are unlikely to play direct roles in pathogenesis. However, these molecules have pleiotropic effects that impact on cancer pathobiology in animal models, and there is evidence that they may do the same in humans. Given their protean properties, chemokines could have tumor-
Ilaria, Conti, Barrett J, Rollins
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Synthesis of aromatic compounds of types ArCH2CH = CCl2 and Ar?(CH2CH = CCl2)2

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1959
1. The condensation of 1,1,3-trichloro-1-propene with benzene, toluene, 3-phenyl-1,1-dichloro-1-propene, 3-(p-chlorophenyl)-1,1-dichloro-1-propene, naphthalene and 3-phenyl-1,1,1,2-tetrachloropropane was carried out in the presence of aluminum chloride or antimony pentachloride, with the formation of the corresponding mono- and di-alkylated products.
R. Kh. Freidlina, N. A. Semenov, A. N. Nesmeyanov   +2 more
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Kinetics of the CCl2+ Br2 and CCl2+ NO2 reactions in the temperature range 266−365 K and reactivity of the CCl2 biradical

Chemical Physics Letters, 2008
Abstract The kinetics of the CCl2 + Br2 and CCl2 + NO2 reactions have been studied at temperatures between 266 and 365 K using laser photolysis/photoionization mass spectrometry. Dichloromethylene biradicals were produced by the pulsed laser photolysis of CCl4.
Arkke J. Eskola, Iwona Golonka, Matti P. Rissanen, Raimo S. Timonen   +3 more
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TRPV1 receptor inhibition decreases CCL2-induced hyperalgesia

Neuropharmacology, 2014
Modulation of nociceptive synaptic transmission in the spinal cord is implicated in the development and maintenance of several pathological pain states. The chemokine CCL2 (C-C motif ligand 2) was shown to be an important factor in the development of neuropathic pain after peripheral nerve injury.
Diana, Spicarova, Pavel, Adamek, Nataliia, Kalynovska, Petra, Mrozkova, Jiri, Palecek   +4 more
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Stimulation of CCL2 (MCP-1) and CCL2 mRNA by substance P in LAD2 human mast cells

Translational Research, 2009
Chemokines are cytokines with chemotactic properties on inflammatory cells and other cell types. Chemokine (C-C motif) ligand 2 (CCL2), which is also called monocyte chemotactic protein 1 (MCP-1), is a potent chemotactic molecule that attracts lymphocytes, monocytes, mast cells, and memory T cells, but not neutrophils.
Castellani ML, VECCHIET, Jacopo, SALINI, VINCENZO, Conti P, Theoharides TC, Caraffa A, Antinolfi P, TETE', Stefano, Ciampoli C, CUCCURULLO, CHIARA, Cerulli G, FELACO, Mario, BOSCOLO, Paolo   +12 more
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CCL2/CCR2 signaling pathway in glioblastoma multiforme

Neurochemistry International, 2017
Glioblastoma multiform (GBM) is described as one of the most frequent primary brain tumors. These types of malignancies constitute only 15% of all primary brain tumors. Despite, extensive developments on effective therapeutic methods during the 20th century as well as the first decade of the present century (21st), the median survival rate for patients
Alireza, Vakilian, Hossein, Khorramdelazad, Parisa, Heidari, Zahra, Sheikh Rezaei, Gholamhossein, Hassanshahi   +4 more
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CCL2 DNA vaccine to treat renal disease

The International Journal of Biochemistry & Cell Biology, 2009
CCL2 DNA vaccines are directed against the host chemoattractant molecule CCL2 (MCP-1), a key chemokine in recruiting macrophages to sites of inflammation. Macrophages recruited by CCL2 lead to progressive renal injury. In rat models of disease unmodified CCL2 DNA vaccine in combination with a CCL5 (RANTES) DNA vaccine can protect against chronic renal ...
Watson, Debbie, Zheng, Guoping, Wu, Huiling, Wang, Yuan Min, Wang, Yiping, Harris, David C. H, Alexander, S I   +6 more
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Association of CCL2 Gene Variants with Osteoarthritis

Archives of Medical Research, 2019
The chemokine (C-C motif) Ligand 2 (CCL2)/CCR2 signaling was associated with macrophage accumulation, synovitis and cartilage damage in a mouse osteoarthritis (OA) model.Here a case-control study in a Chinese Han population was conducted to investigate the possible association between the CCL2 gene polymorphism and risk of OA.
Zhonghua, Xu, Jin, Li, Haoyu, Yang, Lifeng, Jiang, Xindie, Zhou, Yong, Huang, Nanwei, Xu   +6 more
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Fibroblast-Derived CCL2 Induces Cancer Stem Cells—Letter

Cancer Research, 2013
Tsuyada and colleagues ([1][1]) investigated the effects of cancer-associated fibroblasts (CAF) on cancer stem cells (CSC). In contrast to a number of previous studies that focused only on the intrinsic factors, this study is very unique as it characterizes the factors within the ...
Gunaydin, G., Dolen, Y., Kesikli, S.A.
openaire   +3 more sources