Results 131 to 140 of about 39,533 (201)
Journal of Pain Research, 2018 Yi-Li Zhang,1,2,* Bei Li,1,2,* Zeng-Huan Zhou1 1School of Public Health, Southern Medical University, Guangzhou, Guangdong Province, People’s Republic of China; 2School of Health Services Management, Southern Medical University, Guangzhou ...
Zhang YL, Li B, Zhou ZH
doaj
MedComm, Volume 7, Issue 10, October 2026.This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.This prospective single‐arm study evaluated neoadjuvant disitamab vedotin plus penpulimab in 20 patients with Stage II–III HER2‐low breast cancer. The regimen showed preliminary activity (pCR 20.0% intention‐to‐treat, 25.0% evaluable; ORR 56.3%) with manageable toxicity.
Xiaoxiao Liu +17 more
wiley +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Influência aa proteína inflamatória de macrófagos CCL3 em camundongos C57Bl/6J infectados com Fasciola hepatica. [PDF]
, 2007 Fasciola hepatica é um helminto que parasita fígado e vias biliares de bovinos, ovinos e caprinos, entre outros, com marcantes prejuízos para a pecuária das regiões sul e sudeste do Brasil devido à sua patogenia.
Renata Cristina de Paula
core
MedComm, Volume 7, Issue 10, October 2026.BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley +1 more source
Liver Metastases from Colorectal Cancer: From Pathogenesis to Current Treatment
MedComm, Volume 7, Issue 10, October 2026.The liver is not merely a passive recipient of disseminated tumor cells, but a unique metastatic organ shaped by anatomical, metabolic, and immunological characteristics that support tumor colonization. Increasing evidence indicates that colorectal cancer liver metastasis development is driven by dynamic interactions between tumor intrinsic programs ...
Jialiang Fan +10 more
wiley +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.Using 38 blood SASP proteins, a guided autoencoder‐transformer model generates a composite SASP Score that captures systemic cellular senescence burden. The score predicts mortality and age‐related diseases, outperforms individual proteins, and supports cross‐platform biomarker translation.
Shangshu Zhao +9 more
wiley +1 more source
Multimodal Ageing Biomarkers and Plasma Proteomic Signatures Associated With All‐Cause Mortality
Aging Cell, Volume 25, Issue 10, October 2026.We benchmarked 23 ageing biomarkers and 9703 protein targets for associations with mortality risk. Epigenetic, neuroimaging and functional biomarkers showed the strongest associations, outperforming proteomic organ clocks. Among 368 mortality‐associated proteins, high‐risk proteins were enriched in immune functions, whereas low‐risk proteins were ...
Maira Pyrgioti +14 more
wiley +1 more source
Experimental Physiology, Volume 111, Issue 10, Page 4705-4721, 1 October 2026.Abstract Cancer cachexia, affecting up to 80% of patients with advanced cancer, is characterized by metabolic and inflammatory dysregulation driven by tumour‐ and host‐derived factors. Although cytokines are central to cachexia pathogenesis, their circulating profiles and transcriptional relevance across models and sexes remain incompletely defined. We
Francielly Morena +8 more
wiley +1 more source