Results 91 to 100 of about 4,207 (232)

CCM signaling complex (CSC) couples both classic and non-classic Progesterone receptor signaling

Cell Communication and Signaling, 2022
Background Breast cancer, the most diagnosed cancer, remains the second leading cause of cancer death in the United States, and excessive Progesterone (PRG) or Mifepristone (MIF) exposure may be at an increased risk for developing breast cancer.
Johnathan Abou-Fadel, Xiaoting Jiang, Brian Grajeda, Akhil Padarti, Cameron C. Ellis, Esmeralda Flores, Alyssa-Marie D. Cailing-De La O, Jun Zhang   +7 more
doaj   +1 more source

The relative roles of CO2 and palaeogeography in determining Late Miocene climate: results from a terrestrial model-data comparison [PDF]

, 2012
The Late Miocene (∼11.6–5.3 Ma) palaeorecord provides evidence for a warmer and wetter climate than that of today and there is uncertainty in the palaeo-CO2 record of at least 150 ppmv.
Bradshaw, Catherine, Eronen, Jussi, Flecker, Rachel, Haywood, Alan, Lunt, Daniel, Pound, Matthew, Salzmann, Ulrich   +6 more
core   +2 more sources

Diversity and structural‐functional insights of alpha‐solenoid proteins

Protein Science, Volume 33, Issue 11, November 2024.
Abstract Alpha‐solenoids are a significant and diverse subset of structured tandem repeat proteins (STRPs) that are important in various domains of life. This review examines their structural and functional diversity and highlights their role in critical cellular processes such as signaling, apoptosis, and transcriptional regulation.
Paula Nazarena Arrías, Zarifa Osmanli, Estefanía Peralta, Patricio Manuel Chinestrad, Alexander Miguel Monzon, Silvio C. E. Tosatto   +5 more
wiley   +1 more source

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation

Frontiers in Neurology, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities.
Christian Thomas, Andrea Zühlsdorf, Konstanze Hörtnagel, Lejla Mulahasanovic, Oliver M. Grauer, Philipp Kümpers, Heinz Wiendl, Sven G. Meuth   +7 more
doaj   +1 more source

Anisotropic Third Harmonic Generation in 2D Tin Sulfide

Advanced Optical Materials, Volume 12, Issue 29, October 15, 2024.
The inherent in‐plane anisotropic properties of 2D SnS offer a unique degree of freedom advantageous for optoelectronic applications. In this study, it is demonstrated that the third harmonic generation (THG) from ultrathin SnS exhibits significant in‐plane anisotropy. By calculating the relative magnitudes of the χ(3) tensor components and determining
George Miltos Maragkakis, Sotiris Psilodimitrakopoulos, Leonidas Mouchliadis, Abdus Salam Sarkar, Andreas Lemonis, George Kioseoglou, Emmanuel Stratakis   +6 more
wiley   +1 more source

Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation. [PDF]

, 2012
International audienceABSTRACT: The Blood--brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and ...
Artus, Cédric, Couraud, Pierre-Olivier, Ganeshamoorthy, Kayathiri, Glacial, Fabienne, Luissint, Anny-Claude   +4 more
core   +4 more sources

Multilayer Core‐Shell Fiber Device for Improved Strain Sensing and Supercapacitor Applications

Small, Volume 20, Issue 38, September 19, 2024.
A unique, flexible, and durable fiber is created by the blending of materials such as carbon nanotubes, MXene, and cotton through a process known as dry spinning. Highly sensitive to small stretches and excelling in energy storage, this innovative fiber surpasses ordinary fibers. It has been shown to perform well under various environmental conditions,
Md Milon Hossain, Patrapee Kungsadalpipob, Nanfei He, Wei Gao, Philip Bradford   +4 more
wiley   +1 more source

Schizosaccharomyces pombe as a fundamental model for research on mitochondrial gene expression: Progress, achievements and outlooks

IUBMB Life, Volume 76, Issue 7, Page 397-419, July 2024.
Abstract Schizosaccharomyces pombe (fission yeast) is an attractive model for mitochondrial research. The organism resembles human cells in terms of mitochondrial inheritance, mitochondrial transport, sugar metabolism, mitogenome structure and dependence of viability on the mitogenome (the petite‐negative phenotype).
Nhu Dinh, Nathalie Bonnefoy
wiley   +1 more source

A novel CCM2 gene mutation associated with family cerebral cavernous malformation

Frontiers in Aging Neuroscience, 2016
Background: Cerebral cavernous malformations (CCMs) are common vascular malformations that predominantly arise in the central nervous system and are mainly characterized by enlarged vascular cavities without intervening brain parenchyma.
Wen-Qing Huang, Wen-Qing Huang, Cong-Xia Lu, Ya Zhang, Ya Zhang, Ke-Hui Yi, Liang-Liang Cai, Liang-Liang Cai, Ming-Li Li, Ming-Li Li, Han Wang, Han Wang, Qing Lin, Qing Lin, Chi-Meng Tzeng, Chi-Meng Tzeng, Chi-Meng Tzeng   +16 more
doaj   +1 more source

Comparative omics of CCM signaling complex (CSC)

Chinese Neurosurgical Journal, 2020
Background Cerebral cavernous malformations (CCMs), a major neurosurgical condition, characterized by abnormally dilated intracranial capillaries, result in increased susceptibility to stroke.
Johnathan Abou-Fadel, Mark Smith, Kamran Falahati, Jun Zhang   +3 more
doaj   +1 more source