Results 81 to 90 of about 3,591 (208)

ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish [PDF]

open access: yesHuman Molecular Genetics, 2008
Cerebral cavernous malformations (CCMs) are a prevalent class of vascular anomalies characterized by thin-walled clusters of malformed blood vessels in the brain. Heritable forms are caused by mutations in CCM1, CCM2 and CCM3, but despite the importance of these factors in vascular biology, an understanding of their molecular and cellular functions ...
Hogan, Benjamin M.   +3 more
openaire   +5 more sources

GERM-LINE/SOMATIC DNA COMPARISON IN SPORADIC PATIENTS WITH CEREBRAL CAVERNOUS MALFORMATIONS.

open access: yesEuromediterranean Biomedical Journal, 2017
Cerebral cavernous malformations (CCMs) are benign tumours that affect brain capillaries. Although many cases remain asymptomatic, their incidence is steadily increasing.
Ivan Anchesi
doaj   +1 more source

Quantum complementarity of microcavity polaritons [PDF]

open access: yes, 2005
We present an experiment that probes polariton quantum correlations by exploiting quantum complementarity. Specifically, we find that polaritons in two distinct idler-modes interfere if and only if they share the same signal-mode so that "which-way ...
M. O. Scully   +4 more
core   +4 more sources

CELS‐3D—Cutting edge light source for exciting fluorescence in microtome‐based 3D microscopy and targeted correlative microscopy

open access: yesJournal of Anatomy, Volume 246, Issue 5, Page 782-797, May 2025.
A working prototype of a novel 3D fluorescent microscope, designated CELS‐3D (Cutting Edge Light Source, Three‐Dimensional), was constructed and the proof of principle demonstrated. The light originating from the cutting edge of the glass knife forms a kind of light sheet suitable for fluorescence excitation and 3D imaging of fluorescent samples.
Vladyslav Denyshchenko   +7 more
wiley   +1 more source

The function and regulation of CIA5/CCM1 in Chlamydomonas reinhardtii

open access: yes, 2018
We demonstrate that CIA5, the master CCM transcription regulator of the Chlamydomonas CCM, has transcription activation activity either in yeast or in Chlamydomonas, and has an acidic activation domain that also is responsible for abnormal SDS-PAGE migration. We are also the first successful overexpression and purification of CIA5 protein from E. coli.,
openaire   +3 more sources

CCM signaling complex (CSC) couples both classic and non-classic Progesterone receptor signaling

open access: yesCell Communication and Signaling, 2022
Background Breast cancer, the most diagnosed cancer, remains the second leading cause of cancer death in the United States, and excessive Progesterone (PRG) or Mifepristone (MIF) exposure may be at an increased risk for developing breast cancer.
Johnathan Abou-Fadel   +7 more
doaj   +1 more source

Links between topography, wind, deflation, lakes and dust: The case of the Bodélé Depression, Chad [PDF]

open access: yes, 2006
The Bodélé Depression, Chad is the planet's largest single source of dust. Deflation from the Bodélé could be seen as a simple coincidence of two key prerequisites: strong surface winds and a large source of suitable sediment.
A. S. Goudie   +38 more
core   +4 more sources

Periodic Light Modulations for Low‐Cost Wide‐Field Imaging of Luminescence Kinetics Under Ambient Light

open access: yesAdvanced Science, Volume 12, Issue 10, March 13, 2025.
Imaging fast luminescence kinetics has required costly camera setups. The RIOM and HIOM protocols relying on modulated illumination are introduced to make this possible with standard low‐cost cameras, even under ambient light. These are implemented to measure the photoactivation time of a reversibly photoswitchable protein and microsensors and recover ...
Hélène Merceron   +5 more
wiley   +1 more source

A Novel PKD1 Mutation Associated With Autosomal Dominant Kidney Disease and Cerebral Cavernous Malformation

open access: yesFrontiers in Neurology, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the presence of renal cysts and specific extrarenal abnormalities.
Christian Thomas   +7 more
doaj   +1 more source

Birth of Cities: Division of Labor and Transportation Costs [PDF]

open access: yes, 2014
In this paper, we constructs a model with two-region, two sector and two types of workers. One type of workers has a comparative advantage in agricultural production and mobile between two regions, while the other type of workers has a comparative ...
morita, tadashi, yamamoto, kazuhiro
core  

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