Results 61 to 70 of about 2,140 (195)
ABSTRACT Background Cerebral cavernous malformations (CCM) are vascular lesions prone to hemorrhage, but the influence of modifiable cardiovascular risk factors and commonly prescribed therapies on bleeding risk remains unclear. Methods We performed a systematic review and meta‐analysis according to PRISMA 2020.
Sai Sanikommu +10 more
wiley +1 more source
Enhanced Yes-associated protein (YAP)/transcriptional co-activator with PDZ-binding motif (TAZ) signaling is correlated with the extraprostatic extension of prostate cancer. However, the mechanism by which YAP/TAZ signaling becomes hyperactive and drives
Jaehong Kim +6 more
core +1 more source
Coexistence of Ebstein Anomaly and Cerebral Cavernous Malformation: A Case Report
ABSTRACT In most patients who have Ebstein anomaly (EA), neurological symptoms are either associated with thromboembolic episodes or due to arrhythmic complications. Cerebral cavernous malformation (CCM) is a vascular anomaly made up of sinusoidally dilated blood vessels, often presenting with seizure activity or intracranial bleeding.
Nazmin Ahmed +5 more
wiley +1 more source
A novel KRIT1 initiation‐region frameshift variant, NM_004912.4.2dup [p.(Met1IlefsTer31)], was identified in a pediatric family with familial cerebral cavernous malformation. Marked intrafamilial variability supports early molecular diagnosis, cascade family screening, and susceptibility‐sensitive MRI surveillance. ABSTRACT Background Familial cerebral
Özlem Yayıcı Köken +5 more
wiley +1 more source
Cerebral cavernous malformations (CCMs) are vascular abnormalities that primarily occur in adulthood and cause cerebral hemorrhage, stroke, and seizures.
Huanjiao Jenny Zhou +10 more
doaj +1 more source
Negatively charged boron vacancy defects in hexagonal boron nitride promise near‐surface quantum sensing, but their internal spin transition rates are only partly understood. This work directly measures the defect's singlet‐state lifetime, 15(3) ns, using a nanosecond rise‐time dual‐pulse photoluminescence‐recovery method, and shows that high laser ...
Richard A. Escalante +11 more
wiley +1 more source
Sequencing of exon 5 (reverse strand, CCM1) of CV126 index patient showing mutation c.618_619delinsG.
Francisca Solano (513838) +9 more
core +1 more source
Kavernome sind vaskuläre Neubildungen im zentralen Nervensystem, welche aus dilatierten, dünnwandigen, sinusoidalen Blutgefäßen bestehen. Histologisch zeigen sich nur anormal vorhandene oder gänzlich fehlende Tight Junctions der Endothelzellen und ...
Hansen, Bodil (138690723)
core +2 more sources
Next-Generation Sequencing Advances the Genetic Diagnosis of Cerebral Cavernous Malformation (CCM)
Cerebral Cavernous Malformation (CCM) is a cerebrovascular disease of genetic origin that predisposes to seizures, focal neurological deficits and fatal intracerebral hemorrhage. It may occur sporadically or in familial forms, segregating as an autosomal
Valerio Benedetti +6 more
doaj +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source

