Results 41 to 50 of about 3,591 (208)
The effect of different hydration media on magnesia
Discover Materials, 2021 This paper discusses the rate of hydration of magnesia (CCM1 and CCM2) during the formation of magnesium hydroxide with magnesium acetate and distilled water.
Friedrich von Hoessle +5 more
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KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell–cell junctions [PDF]
The Journal of Cell Biology, 2007 Cerebral cavernous malformation (CCM), a disease associated with defective endothelial junctions, result from autosomal dominant CCM1 mutations that cause loss of KRIT-1 protein function, though how the loss of KRIT-1 leads to CCM is obscure. KRIT-1 binds to Rap1, a guanosine triphosphatase that maintains the integrity of endothelial junctions.
Glading, Angela +3 more
openaire +4 more sources
Diagnóstico molecular de cavernomatosis cerebral
Neurología, 2017 Resumen: Introducción: Las malformaciones cavernosas cerebrales (CCM; OMIM 116860) son engrosamientos cavernosos vasculares sin intervención del parénquima cerebral con una prevalencia estimada en la población general del 0,1-0,5%.
R. Mondejar, M. Lucas
doaj +1 more source
Cells, 2021 Cerebral cavernous malformations (CCMs) are vascular lesions that affect predominantly microvasculature in the brain and spinal cord. CCM can occur either in sporadic or familial form, characterized by autosomal dominant inheritance and development of ...
Giulia Riolo +2 more
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Spanish families with cavernous angiomas do not share the Hispano- American CCM1 haplotype [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1999 Cerebral cavernous malformations are vascular malformations mostly located in the CNS. Their frequency is estimated close to 0.5% in the general population.1 Cerebral cavernous malformations occur as a sporadic or hereditary condition. From the Hispano-American population, familial forms were reported with a high frequency.2 CCM1 , a hitherto ...
H H, Jung +9 more
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Molecular diagnosis in cerebral cavernous malformations
Neurología (English Edition), 2017 Introduction: Cerebral cavernous malformations (CCMs; OMIM 116860) are enlarged vascular cavities without intervening brain parenchyma whose estimated prevalence in the general population is between 0.1% and 0.5%.
R. Mondejar, M. Lucas
doaj +1 more source
A Novel CCM2 Gene Mutation Associated With Cerebral Cavernous Malformation
Frontiers in Neurology, 2020 Cerebral cavernous malformations (CCMs) are the second most prevalent type of vascular malformation within the central nervous system. CCMs occur in two forms—sporadic and familial—the latter of which has an autosomal dominant mode of inheritance with ...
Lipeng Yang, Jian Wu, Jing Zhang
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Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. [PDF]
, 2016 Heart of Glass (HEG1), a transmembrane receptor, and Rasip1, an endothelial-specific Rap1-binding protein, are both essential for cardiovascular development.
de Kreuk, Bart-Jan +5 more
core +2 more sources
Ccm1is required for arterial morphogenesis: implications for the etiology of human cavernous malformations [PDF]
Development, 2004 Hemorrhagic stroke is a significant cause of morbidity and mortality in children, and is frequently associated with intracranial vascular malformations. One prevalent form of these vascular malformations, cerebral cavernous malformation, is characterized by thin-walled vascular cavities that hemorrhage and has been linked to loss-of-function mutations ...
Kevin J, Whitehead +4 more
openaire +2 more sources
Biomedicines, 2023 Cerebral cavernous malformation (CCM) or cavernoma is a major vascular disease of genetic origin, whose main phenotypes occur in the central nervous system, and is currently devoid of pharmacological therapeutic strategies.
Andrea Perrelli +7 more
doaj +1 more source