Results 91 to 100 of about 3,591 (208)

CCM1 and CCM2 variants in patients with cerebral cavernous malformation in an ethnically Chinese population in Taiwan [PDF]

Scientific Reports, 2019
AbstractCerebral cavernous malformation (CCM) is a vascular malformation characterized by clustered enlarged capillary-like channels in the central nervous system. The genes harboring variants in patients with CCM includeCCM1/Krev interaction trapped-1,CCM2/MGC4607, andCCM3/programmed cell death protein 10.
Chun-Wei Chang, Peng-Wei Hsu, Kuo-Chen Wei, Chia-Wen Chang, Hon-Chung Fung, Mo-Song Hsih, Wen-Chuin Hsu, Long-Sun Ro, Chen-Nen Chang, Jiun-Jie Wang, Yih-Ru Wu, Sien-Tsong Chen   +11 more
openaire   +2 more sources

Transfer morphological features for segmentation with few labels on fluorescent mitochondria images

IET Image Processing, Volume 19, Issue 1, January/December 2025.
Deep learning‐based approaches have demonstrated promising performance; however, the scarcity of labeled mitochondrial data presents a significant challenge. To address this, we propose a high‐precision segmentation framework leveraging inductive transfer learning.
Tianyi Zhang, Junchao Fan, Xiuli Bi, Weisheng Li, Bin Xiao, Xiaoshuai Huang   +5 more
wiley   +1 more source

Zebrafish models of cerebrovascular disease [PDF]

, 2014
Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a heterogeneous group of disease ...
Peterson, Randall T, Walcott, Brian P
core   +1 more source

A novel CCM2 gene mutation associated with family cerebral cavernous malformation

Frontiers in Aging Neuroscience, 2016
Background: Cerebral cavernous malformations (CCMs) are common vascular malformations that predominantly arise in the central nervous system and are mainly characterized by enlarged vascular cavities without intervening brain parenchyma.
Wen-Qing Huang, Wen-Qing Huang, Cong-Xia Lu, Ya Zhang, Ya Zhang, Ke-Hui Yi, Liang-Liang Cai, Liang-Liang Cai, Ming-Li Li, Ming-Li Li, Han Wang, Han Wang, Qing Lin, Qing Lin, Chi-Meng Tzeng, Chi-Meng Tzeng, Chi-Meng Tzeng   +16 more
doaj   +1 more source

Comparative omics of CCM signaling complex (CSC)

Chinese Neurosurgical Journal, 2020
Background Cerebral cavernous malformations (CCMs), a major neurosurgical condition, characterized by abnormally dilated intracranial capillaries, result in increased susceptibility to stroke.
Johnathan Abou-Fadel, Mark Smith, Kamran Falahati, Jun Zhang   +3 more
doaj   +1 more source

Equatorial waves simulated by the NCAR community climate model [PDF]

The equatorial planetary waves simulated by the NCAR CCM1 general circulation model were investigated in terms of space-time spectral analysis (Kao, 1968; Hayashi, 1971, 1973) and energetic analysis (Hayashi, 1980).
Chen, Tsing-Chang, Cheng, Xinhua
core   +1 more source

Integral group actions on symmetric spaces and discrete duality symmetries of supergravity theories [PDF]

, 2015
For $G(\mathbb{R})$ a split, simply connected, semisimple Lie group of rank $n$ and $K$ the maximal compact subgroup of $G$, we give a method for computing Iwasawa coordinates of $G/K$ using the Chevalley generators and the Steinberg presentation.
Cacciatori S. L., Carbone L., Carter R. W., Cremmer E., Hisham Sati, Lisa Carbone, Olive D., Scott H. Murray, Soulé C., Steinberg R.   +9 more
core   +1 more source

Diversity and structural‐functional insights of alpha‐solenoid proteins

Protein Science, Volume 33, Issue 11, November 2024.
Abstract Alpha‐solenoids are a significant and diverse subset of structured tandem repeat proteins (STRPs) that are important in various domains of life. This review examines their structural and functional diversity and highlights their role in critical cellular processes such as signaling, apoptosis, and transcriptional regulation.
Paula Nazarena Arrías, Zarifa Osmanli, Estefanía Peralta, Patricio Manuel Chinestrad, Alexander Miguel Monzon, Silvio C. E. Tosatto   +5 more
wiley   +1 more source

Research on diabatic initialization [PDF]

The objective of this research is to contribute to the improvement of the analyses of irrotational wind and moisture fields in the tropics through advancement in the technique of initialization, incorporating diabatic effects and use of satellite-derived,
Kashara, Akira
core   +5 more sources

A novel CCM2 variant in a family with non-progressive cognitive complaints and cerebral microbleeds [PDF]

, 2017
Lobar cerebral microbleeds are most often sporadic and associated with Alzheimer's disease. The aim of our study was to identify the underlying genetic defect in a family with cognitive complaints and multiple lobar microbleeds and a positive family ...
Barkhof, F. (Frederik), Cohn-Hokke, P.E. (P.), Flier, W.M. (Wiesje) van der, Holstege, H. (Henne), Meijers-Heijboer, E.J. (Hanne), Pijnenburg, Y.A.L. (Yolande), Scheltens, P. (Philip), Sistermans, E.A. (Erik), Swieten, J.C. (John) van, Weiss, M.M. (Marjan M.)   +9 more
core   +1 more source