Results 41 to 50 of about 7,007 (197)

High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

open access: yesBMC Genomics, 2012
Background In Bacillus subtilis and its relatives carbon catabolite control, a mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism, is achieved by the global regulator CcpA (carbon catabolite protein A).
Marciniak Bogumiła C   +6 more
doaj   +1 more source

CcpA Mediates the Catabolite Repression of tst in Staphylococcus aureus [PDF]

open access: yesInfection and Immunity, 2008
ABSTRACT Some clinical isolates of Staphylococcus aureus produce the superantigenic toxic shock syndrome toxin 1 (TSST-1), encoded by tst , located on pathogenicity islands. The expression of tst is complex and is influenced by environmental conditions such ...
Seidl, K, Bischoff, M, Berger-Bächi, B
openaire   +4 more sources

CcpA-Dependent Carbon Catabolite Repression Regulates Fructooligosaccharides Metabolism in Lactobacillus plantarum

open access: yesFrontiers in Microbiology, 2018
Fructooligosaccharides (FOSs) metabolism in Lactobacillus plantarum is controlled by two gene clusters, and the global regulator catabolite control protein A (CcpA) may be involved in the regulation. To understand the mechanism, this study focused on the
Chen Chen   +4 more
doaj   +1 more source

Impact of the Histidine-Containing Phosphocarrier Protein HPr on Carbon Metabolism and Virulence in Staphylococcus aureus

open access: yesMicroorganisms, 2021
Carbon catabolite repression (CCR) is a common mechanism pathogenic bacteria use to link central metabolism with virulence factor synthesis. In gram-positive bacteria, catabolite control protein A (CcpA) and the histidine-containing phosphocarrier ...
Linda Pätzold   +6 more
doaj   +1 more source

Verification of CcpA gene knockout

open access: yes, 2021
To verify whether the CcpA gene was successfully deleted, we designed the primer for PCR. The primer was designed across the upstream and downstream sequences of the CcpA gene, with a size of about 1827bp. Results showed that two (1827bp and 1985bp) PCR products (WT2 and KO2) were produced, then the amplified DNA products of WT2 and KO2 were ...
openaire   +1 more source

CcpA and CodY Coordinate Acetate Metabolism in Streptococcus mutans [PDF]

open access: yesApplied and Environmental Microbiology, 2017
ABSTRACT In the dental caries pathogen Streptococcus mutans , phosphotransacetylase (Pta) and acetate kinase (Ack) convert pyruvate into acetate with the concomitant generation of ATP. The genes for this pathway are tightly regulated by multiple environmental and intracellular inputs, but the basis for ...
Jeong Nam Kim, Robert A. Burne
openaire   +2 more sources

On the Phase Width of MgZn2/KHg2‐Type Intermetallics AIIMg2−xZnx (A = Ca, Sr, Ba) and the New Compounds (Sr/Ba)11Mg16Zn6 and Ba6Mg2.8Zn8.2

open access: yesZeitschrift für anorganische und allgemeine Chemie, EarlyView.
The continuous, but obviously geometrically limited Mg↔Zn substitution in members of the two basic structures types of intermetallics, the KHg2‐type dizincides, and the MgZn2/Laves‐type dimagnesidesof Ca, Sr, and Ba exhibit a large phase widths for CaMg2 only. Instead, the larger alkaline‐earth elements form the “optimized” complex compounds A11Mg16Zn6
Katharina Köhler   +4 more
wiley   +1 more source

Effects of ccpA gene deficiency in Lactobacillus delbrueckii subsp. bulgaricus under aerobic conditions as assessed by proteomic analysis

open access: yesMicrobial Cell Factories, 2020
Background Aerobic growth provides benefits in biomass yield and stress tolerance of Lactobacillus delbrueckii subsp. bulgaricus (L. bulgaricus). Catabolite control protein A (CcpA) is a master regulator involved in the aerobic and anaerobic growth ...
Guofang Zhang, Libo Liu, Chun Li
doaj   +1 more source

Ribozyme-Mediated Downregulation Uncovers DNA Integrity Scanning Protein A (DisA) as a Solventogenesis Determinant in Clostridium beijerinckii

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Carbon catabolite repression (CCR) limits microbial utilization of lignocellulose-derived pentoses. To relieve CCR in Clostridium beijerinckii NCIMB 8052, we sought to downregulate catabolite control protein A (CcpA) using the M1GS ribozyme technology. A
Victor Chinomso Ujor   +4 more
doaj   +1 more source

Do Tech‐Based New Ventures Founded During Major Economic Crises Generate Different R&D Outputs?

open access: yesJournal of Product Innovation Management, EarlyView.
ABSTRACT Tech‐based ventures—regardless of external circumstances—must allocate resources to research and development (R&D) activities to satisfy their raison d'être and establish their market positioning. When founded during economic crises, these ventures encounter distinctive opportunities but also face resource scarcity, both of which significantly
Philip Haeberle   +3 more
wiley   +1 more source

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