Transcriptome Analysis Reveals Catabolite Control Protein A Regulatory Mechanisms Underlying Glucose-Excess or -Limited Conditions in a Ruminal Bacterium, Streptococcus bovis [PDF]
Frontiers in Microbiology, 2021 Ruminants may suffer from rumen acidosis when fed with high-concentrate diets due to the higher proliferation and overproduction of lactate by Streptococcus bovis.
Yaqian Jin +4 more
doaj +2 more sources
The Role of Regulator Catabolite Control Protein A (CcpA) in Streptococcus agalactiae Physiology and Stress Response [PDF]
Microbiology Spectrum, 2022 Streptococcus agalactiae is a leading cause of infections in neonates. This opportunistic pathogen colonizes the vagina, where it has to cope with acidic pH and hydrogen peroxide produced by lactobacilli.
Anne-Emmanuelle Roux +7 more
doaj +2 more sources
Transcriptional regulation of cellobiose utilization by PRD-domain containing Sigma54-dependent transcriptional activator (CelR) and catabolite control protein A (CcpA) in Bacillus thuringiensis [PDF]
Frontiers in MicrobiologyCellobiose, a β-1,4-linked glucose dimer, is a major cellodextrin resulting from the enzymatic hydrolysis of cellulose. It is a major source of carbon for soil bacteria.
Liangwei Zhang +5 more
doaj +2 more sources
Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation. [PDF]
J Biol Chem, 2022 Liao X +9 more
europepmc +2 more sources
Pleiotropic functions of catabolite control protein CcpA in Butanol-producing
BMC Genomics, 2012 Background Clostridium acetobutylicum has been used to produce butanol in industry. Catabolite control protein A (CcpA), known to mediate carbon catabolite repression (CCR) in low GC gram-positive bacteria, has been identified and characterized in C ...
Ren Cong +6 more
doaj +2 more sources
Structure-Based Strategy Reveals a Novel Ligand Binding Site in Staphylococcus aureus Catabolite Control Protein A: Implications for Transcriptional Regulation and Drug Design [PDF]
ACS OmegaAndré Borges Farias +4 more
doaj +2 more sources
Frontiers in Microbiology, 2023 In the opportunistic human pathogen Pseudomonas aeruginosa (Pae), carbon catabolite repression (CCR) orchestrates the hierarchical utilization of N and C sources, and impacts virulence, antibiotic resistance and biofilm development.
Elisabeth Sonnleitner +11 more
doaj +1 more source
Antibiotics, 2022 Staphylococcus aureus represents a notorious opportunistic pathogen causing various infections in biofilm nature, imposing remarkable therapeutic challenges worldwide.
Mingxia Zheng +9 more
doaj +1 more source
Surfactin: A Quorum-Sensing Signal Molecule to Relieve CCR in Bacillus amyloliquefaciens
Frontiers in Microbiology, 2020 Bacillus utilize preferred sugars such as glucose over other carbon sources due to carbon catabolite repression (CCR). Surfactin is a small signal molecule to regulate the quorum-sensing (QS) response such as biofilm formation and sporulation in B ...
Bing Chen +4 more
doaj +1 more source
BMC Microbiology, 2021 Background Catabolite control protein A (CcpA) regulates the transcription of lactate dehydrogenase and pyruvate formate-lyase in Streptococcus bovis, but knowledge of its role in response to different pH is still limited.
Yaqian Jin +5 more
doaj +1 more source