Results 41 to 50 of about 116,634,288 (141)

The Lactobacillus plantarum ftsH gene is a novel member of the CtsR stress response regulon [PDF]

open access: yes, 2008
FtsH proteins have dual chaperone-protease activities and are involved in protein quality control under stress conditions. Although the functional role of FtsH proteins has been clearly established, the regulatory mechanisms controlling ftsH expression ...
D. Fiocco   +28 more
core   +1 more source

CcpA promotes Staphylococcus aureus virulence by directly controlling staphyloxanthin production

open access: yesmLife
Staphylococcus aureus is a notorious opportunistic pathogen with remarkable adaptability, enabling it to infect virtually every human tissue. Staphyloxanthin (STX), a critical virulence factor, contributes to S. aureus oxidative damage.
Xian Chen   +12 more
doaj   +1 more source

Small ubiquitin-like modifier protein SUMO enables plants to control growth independently of the phytohormone gibberellin [PDF]

open access: yes, 2014
Plants survive adverse conditions by modulating their growth in response to a changing environment. Gibberellins (GAs) play a key role in these adaptive responses by stimulating the degradation of growth-repressing DELLA proteins.
Bennett, M.   +33 more
core   +1 more source

Ultrasound-assisted extraction of emodin from Rheum officinale Baill and its antibacterial mechanism against Streptococcus suis based on CcpA

open access: yesUltrasonics Sonochemistry
Emodin was extracted from Rheum officinale Baill by ultrasound-assisted extraction (UAE), and ethanol was chosen as the suitable solvent through SEM and molecular dynamic simulation.
Jingwen Bai   +10 more
doaj   +1 more source

The Regulatory Properties of the Ccr4–Not Complex

open access: yesCells, 2020
The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression.
Nafiseh Chalabi Hagkarim, Roger J. Grand
doaj   +1 more source

CcpA-Knockout Staphylococcus aureus Induces Abnormal Metabolic Phenotype via the Activation of Hepatic STAT5/PDK4 Signaling in Diabetic Mice

open access: yesPathogens, 2023
Catabolite control protein A (CcpA), an important global regulatory protein, is extensively found in S. aureus. Many studies have reported that CcpA plays a pivotal role in regulating the tricarboxylic acid cycle and pathogenicity.
Yilang Li   +10 more
doaj   +1 more source

Promoting cytidine biosynthesis by modulating pyrimidine metabolism and carbon metabolic regulatory networks in Bacillus subtilis

open access: yesMicrobial Cell Factories
Background The modification of single or multiple genes via metabolic engineering can lead to the dysregulation of central metabolism and affect bacterial growth and metabolite accumulation.
Xiangjun Zhang   +8 more
doaj   +1 more source

Functional analysis of the role of CcpA in Lactobacillus plantarum grown on fructooligosaccharides or glucose: a transcriptomic perspective

open access: yesMicrobial Cell Factories, 2018
Background The catabolite control protein A (CcpA) is a master regulator of many important cellular processes in Gram-positive bacteria. In Lactobacillus plantarum, CcpA directly or indirectly controls the transcription of a large number of genes that ...
Yanqing Lu   +5 more
doaj   +1 more source

The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import

open access: yesLife Science Alliance, 2023
Yeast cells employ the cytosolic ubiquitin system to increase the capacity of the mitochondrial import machinery during phases of metabolic transitions. Mitochondria play a key role in cellular energy metabolism.
Saskia Rödl   +11 more
doaj   +1 more source

Cyclic AMP Receptor Protein from Yeast Mitochondria [PDF]

open access: yes, 1985
We have identified and characterized a cyclic AMP receptor protein in mitochondria of the yeast Saccharomyces cerevisiae. The binding is specific for cyclic nucleotides, particularly for cyclic AMP which is bound with high affinity (Kd of 10(-9) M) at 1 ...
Rödel, Gerhard   +2 more
core   +1 more source

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