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CcpA Affects Infectivity of Staphylococcus aureus in a Hyperglycemic Environment [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Many bacteria regulate the expression of virulence factors via carbon catabolite responsive elements. In Gram-positive bacteria, the predominant mediator of carbon catabolite repression is the catabolite control protein A (CcpA).
Markus Bischoff   +2 more
exaly   +9 more sources

Probing the regulatory effects of specific mutations in three major binding domains of the pleiotropic regulator CcpA of Bacillus subtilis [PDF]

open access: yesFrontiers in Microbiology, 2015
Carbon catabolite control is required for efficient use of available carbon sources to ensure rapid growth of bacteria. CcpA is a global regulator of carbon metabolism in Gram-positive bacteria like Bacillus subtilis.
Oscar Paul Kuipers, Gerald Seidel
exaly   +5 more sources

A New Mechanism of Carbon Metabolism and Acetic Acid Balance Regulated by CcpA

open access: yesMicroorganisms, 2023
Catabolite control protein A (CcpA) is a critical regulator in Gram-positive bacteria that orchestrates carbon metabolism by coordinating the utilization of different carbon sources.
Guiyang Shi   +2 more
exaly   +3 more sources

CcpA promotes Staphylococcus aureus virulence by directly controlling staphyloxanthin production [PDF]

open access: yesmLife
Staphylococcus aureus is a notorious opportunistic pathogen with remarkable adaptability, enabling it to infect virtually every human tissue. Staphyloxanthin (STX), a critical virulence factor, contributes to S. aureus oxidative damage.
Xian Chen   +12 more
doaj   +2 more sources

Transcriptome, Phenotypic, and Virulence Analysis of Streptococcus sanguinis SK36 Wild Type and Its CcpA-Null Derivative (ΔCcpA)

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Catabolic control protein (CcpA) is linked to complex carbohydrate utilization and virulence factor in many bacteria species, influences the transcription of target genes by many mechanisms.
Luning Sun
exaly   +3 more sources

comCDE (Competence) Operon Is Regulated by CcpA in Streptococcus pneumoniae D39

open access: yesMicrobiology Spectrum, 2023
Natural transformation plays an important role in the formation of drug-resistant bacteria. Exploring the regulatory mechanism of natural transformation can aid the discovery of new antibacterial targets and reduce the emergence of drug-resistant ...
Xuemei Zhang   +2 more
exaly   +3 more sources

CcpA-mediated regulation of cellular energy metabolism in the ruminal bacterium Streptococcus bovis [PDF]

open access: yesMicrobiology Spectrum
This study investigated the cellular energy metabolite profiles of Streptococcus bovis S1. Glucose concentrations of 5 or 50 mM and the presence or absence of ccpA were applied during the cultivation of S. bovis S1. Results revealed the identification of
Yunan Weng   +4 more
doaj   +2 more sources

Phytochemical Supplementation in Grazing Dairy Cows: Effects on Milk Production, Metabolic Status, Hematology, and Postpartum Ovarian Activity [PDF]

open access: yesVeterinary Medicine International
This study evaluated the effects of three treatments in dairy cows under pasture-based systems during the transition and early lactation periods: one group supplemented with a phytochemical mix (polyphenols, curcuminoids, piperine, and trans ...
Manuela Comesaña   +7 more
doaj   +2 more sources

The Role of ccpA in Nitrogen Source-Induced Heat and Oxidative Stress Tolerance Changes in Lacticaseibacillus rhamnosus [PDF]

open access: yesFoods
The viable bacterial count is a crucial quality indicator for lactic acid bacteria (LAB) starters and fermented foods. Metabolic activity is an integral component of stress tolerance pathways.
Mengting Li   +11 more
doaj   +2 more sources

Challenges of Complying with Data Protection and Privacy Regulations [PDF]

open access: yesEAI Endorsed Transactions on Scalable Information Systems, 2021
As we move into a more digitized society, the collection and use of data continues to increase. This influx in data, partnered with challenges complying with data protection and privacy regulations and the absence of a comprehensive global
A. Lonzetta, T. Hayajneh
doaj   +1 more source

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