Results 31 to 40 of about 7,007 (197)

Functional analysis of the role of CcpA in Lactobacillus plantarum grown on fructooligosaccharides or glucose: a transcriptomic perspective

open access: yesMicrobial Cell Factories, 2018
Background The catabolite control protein A (CcpA) is a master regulator of many important cellular processes in Gram-positive bacteria. In Lactobacillus plantarum, CcpA directly or indirectly controls the transcription of a large number of genes that ...
Yanqing Lu   +5 more
doaj   +1 more source

Effect of the flavonoid baicalin on the proliferative capacity of bovine mammary cells and their ability to regulate oxidative stress [PDF]

open access: yesPeerJ, 2019
Background High-yielding dairy cows are prone to oxidative stress due to the high metabolic needs of homeostasis and milk production. Oxidative stress and inflammation are tightly linked; therefore, anti-inflammatory and/or natural antioxidant compounds ...
Marie-Hélène Perruchot   +5 more
doaj   +2 more sources

The Role of Regulator Catabolite Control Protein A (CcpA) in Streptococcus agalactiae Physiology and Stress Response

open access: yesMicrobiology Spectrum, 2022
Streptococcus agalactiae is a leading cause of infections in neonates. This opportunistic pathogen colonizes the vagina, where it has to cope with acidic pH and hydrogen peroxide produced by lactobacilli.
Anne-Emmanuelle Roux   +7 more
doaj   +1 more source

CcpA-independent glucose regulation of lactate dehydrogenase 1 in Staphylococcus aureus. [PDF]

open access: yesPLoS ONE, 2013
Lactate Dehydrogenase 1 (Ldh1) is a key enzyme involved in Staphylococcus aureus NO·-resistance. Full ldh1-induction requires the presence of glucose, and mutants lacking the Carbon-Catabolite Protein (CcpA) exhibit decreased ldh1 transcription and ...
Adrianne K Crooke   +5 more
doaj   +1 more source

Transcriptome Analysis Reveals Catabolite Control Protein A Regulatory Mechanisms Underlying Glucose-Excess or -Limited Conditions in a Ruminal Bacterium, Streptococcus bovis

open access: yesFrontiers in Microbiology, 2021
Ruminants may suffer from rumen acidosis when fed with high-concentrate diets due to the higher proliferation and overproduction of lactate by Streptococcus bovis.
Yaqian Jin   +4 more
doaj   +1 more source

Investigation of carbon catabolite repression in Clostridium beijerinckii NCIMB 8052 [PDF]

open access: yes, 2001
Summary in English.Includes bibliographical references.The substrate basis for the industrial acetone-butanol-ethanol (ABE) fermentations, has been agricultural products rich in starch or sucrose, and employed taxonomically distinct amylolytic and ...
Rafudeen, M S
core   +1 more source

CcpA-Knockout Staphylococcus aureus Induces Abnormal Metabolic Phenotype via the Activation of Hepatic STAT5/PDK4 Signaling in Diabetic Mice

open access: yesPathogens, 2023
Catabolite control protein A (CcpA), an important global regulatory protein, is extensively found in S. aureus. Many studies have reported that CcpA plays a pivotal role in regulating the tricarboxylic acid cycle and pathogenicity.
Yilang Li   +10 more
doaj   +1 more source

Impact of the catabolite control protein CcpA in "Staphylococcus aureus" [PDF]

open access: yes, 2008
The catabolite control protein CcpA is the main regulator of carbon catabolite repression and activation in low-GC Gram-positive bacteria. In the presence of glucose, CcpA regulates gene expression by binding to so-called catabolite responsive elements ...
Seidl, K
core   +2 more sources

A Flexible Binding Site Architecture Provides New Insights into CcpA Global Regulation in Gram-Positive Bacteria

open access: yesmBio, 2017
Catabolite control protein A (CcpA) is the master regulator in Gram-positive bacteria that mediates carbon catabolite repression (CCR) and carbon catabolite activation (CCA), two fundamental regulatory mechanisms that enable competitive advantages in ...
Yunpeng Yang   +6 more
doaj   +1 more source

Regulation of the Bacillus subtilis acetate kinase gene by CcpA [PDF]

open access: yesJournal of Bacteriology, 1993
The Bacillus subtilis gene encoding acetate kinase was identified on the basis of sequence similarity to the Escherichia coli ackA gene and to a second E. coli gene closely related to ackA. Insertional inactivation of this region of the B. subtilis chromosome resulted in the disappearance of acetate kinase enzyme activity in cell extracts.
F J, Grundy   +3 more
openaire   +2 more sources

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