Results 51 to 60 of about 116,634,288 (141)

High- and low-affinity cre boxes for CcpA binding in Bacillus subtilis revealed by genome-wide analysis

open access: yesBMC Genomics, 2012
Background In Bacillus subtilis and its relatives carbon catabolite control, a mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism, is achieved by the global regulator CcpA (carbon catabolite protein A).
Marciniak Bogumiła C   +6 more
doaj   +1 more source

Disruption of the Mammalian Ccr4–Not Complex Contributes to Transcription-Mediated Genome Instability

open access: yesCells, 2023
The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression.
Nafiseh Chalabi Hagkarim   +6 more
doaj   +1 more source

Transcriptome, Phenotypic, and Virulence Analysis of Streptococcus sanguinis SK36 Wild Type and Its CcpA-Null Derivative (ΔCcpA)

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Catabolic control protein (CcpA) is linked to complex carbohydrate utilization and virulence factor in many bacteria species, influences the transcription of target genes by many mechanisms.
Yibo Bai   +5 more
doaj   +1 more source

Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus [PDF]

open access: yes, 2008
Caldicellulosiruptor saccharolyticus is an extremely thermophilic, gram-positive anaerobe which ferments cellulose-, hemicellulose- and pectin-containing biomass to acetate, CO(2), and hydrogen. Its broad substrate range, high hydrogen-producing capacity,
Willquist, Karin   +51 more
core   +1 more source

A Computational Model of the LGI1 Protein Suggests a Common Binding Site for ADAM Proteins [PDF]

open access: yes, 2011
Mutations of human leucine-rich glioma inactivated (LGI1) gene encoding the epitempin protein cause autosomal dominant temporal lateral epilepsy (ADTLE), a rare familial partial epileptic syndrome.
Leonardi, Emanuela   +23 more
core   +1 more source

Maltose and maltodextrin utilization by Listeria monocytogenes depend on an inducible ABC transporter which is repressed by glucose. [PDF]

open access: yesPLoS ONE, 2010
In the environment as well as in the vertebrate intestine, Listeriae have access to complex carbohydrates like maltodextrins. Bacterial exploitation of such compounds requires specific uptake and utilization systems.We could show that Listeria ...
Shubha Gopal   +6 more
doaj   +1 more source

Global transcriptome response in Lactobacillus sakei during growth on ribose

open access: yesBMC Microbiology, 2011
Background Lactobacillus sakei is valuable in the fermentation of meat products and exhibits properties that allow for better preservation of meat and fish. On these substrates, glucose and ribose are the main carbon sources available for growth. We used
Naterstad Kristine   +3 more
doaj   +1 more source

Gene regulation by CcpA and catabolite repression explored by RNA-Seq in Streptococcus mutans. [PDF]

open access: yesPLoS ONE, 2013
A bacterial transcriptome of the primary etiological agent of human dental caries, Streptococcus mutans, is described here using deep RNA sequencing. Differential expression profiles of the transcriptome in the context of carbohydrate source, and of the ...
Lin Zeng   +5 more
doaj   +1 more source

Vancomycin‐intermediate Staphylococcus aureus employs CcpA‐GlmS metabolism regulatory cascade to resist vancomycin

open access: yesMedComm – Future Medicine
Vancomycin (VAN)‐intermediate Staphylococcus aureus (VISA) is a critical cause of VAN treatment failure worldwide. Multiple genetic changes are reportedly associated with VISA formation, whereas VISA strains often present common phenotypes, such as ...
Huagang Peng   +17 more
doaj   +1 more source

Computational prediction of the Crc regulon identifies genus-wide and species-specific targets of catabolite repression control in Pseudomonas bacteria

open access: yesBMC Microbiology, 2010
Background Catabolite repression control (CRC) is an important global control system in Pseudomonas that fine tunes metabolism in order optimise growth and metabolism in a range of different environments. The mechanism of CRC in Pseudomonas spp.
O'Gara Fergal   +3 more
doaj   +1 more source

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