Results 111 to 120 of about 102,648 (260)

Adenosine—A Regulator of Human Testicular Peritubular Cells

open access: yesAndrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz   +12 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero   +5 more
wiley   +1 more source

Determinants of CCT motif specificity in WNK signaling and expansion of CCT like domains

open access: yes
WNK kinases regulate ion transport and cell volume through interactions with partner proteins such as SPAK, OSR1, NRBP and TSC22D proteins. These interactions are mediated by conserved C-terminal (CCT) domains that recognize short sequence motifs, but the rules governing this recognition remain incompletely defined.
German Magana-Avila   +11 more
openaire   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki   +10 more
wiley   +1 more source

Variation in measuring and ophthalmic factors correlating with central corneal thickness in the Northern Finland birth cohort eye study

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess the correlation between optical coherence tomography (OCT) and ultrasound pachymetry (USP) as methods for analysing central corneal thickness (CCT) and to evaluate ophthalmic factors affecting CCT. Methods The eyes of 3070 subjects of the Northern Finland Birth Cohort (NFBC) were examined at the age of 45–49 years.
Tuomas Qvist   +3 more
wiley   +1 more source

Exploring the Feasibility and Acceptability of Compassion and Mindfulness Training for Adolescents With Type 1 Diabetes and Their Caregivers

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To examine the feasibility and acceptability of mindfulness training for adolescents with Type 1 diabetes (T1D) and compassion training for caregivers. Methods Adolescents aged 12–17 years with T1D, and their caregivers were recruited from two diabetes centres between 2022 and 2023 to participate in an eight‐week, online, open‐label course
Emilie Bundgaard Lindkvist   +7 more
wiley   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

open access: yesBrain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma   +12 more
wiley   +1 more source

Multicentre, 2×2 factorial, randomised, open-label trial of neuromodulators and cough control therapy for refractory or unexplained chronic cough: the FORTITUDE trial protocol. [PDF]

open access: yesBMJ Open
Kum E   +21 more
europepmc   +1 more source

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