Adenosine—A Regulator of Human Testicular Peritubular Cells
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz +12 more
wiley +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Determinants of CCT motif specificity in WNK signaling and expansion of CCT like domains
WNK kinases regulate ion transport and cell volume through interactions with partner proteins such as SPAK, OSR1, NRBP and TSC22D proteins. These interactions are mediated by conserved C-terminal (CCT) domains that recognize short sequence motifs, but the rules governing this recognition remain incompletely defined.
German Magana-Avila +11 more
openaire +1 more source
Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki +10 more
wiley +1 more source
Abstract Purpose To assess the correlation between optical coherence tomography (OCT) and ultrasound pachymetry (USP) as methods for analysing central corneal thickness (CCT) and to evaluate ophthalmic factors affecting CCT. Methods The eyes of 3070 subjects of the Northern Finland Birth Cohort (NFBC) were examined at the age of 45–49 years.
Tuomas Qvist +3 more
wiley +1 more source
Integration of CCT/TRiC assembly, degradation and function: Chaperonin complexity in a cellular context. [PDF]
Grantham J.
europepmc +1 more source
ABSTRACT Aim To examine the feasibility and acceptability of mindfulness training for adolescents with Type 1 diabetes (T1D) and compassion training for caregivers. Methods Adolescents aged 12–17 years with T1D, and their caregivers were recruited from two diabetes centres between 2022 and 2023 to participate in an eight‐week, online, open‐label course
Emilie Bundgaard Lindkvist +7 more
wiley +1 more source
Extended Long-Term Effects of Cognitive and Aerobic Training on Cognitive Function in Patients With Stress-Related Exhaustion Disorder: A 4.5-Year Follow-Up of a Randomized Controlled Trial. [PDF]
Aronsson I +4 more
europepmc +1 more source
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma +12 more
wiley +1 more source
Multicentre, 2×2 factorial, randomised, open-label trial of neuromodulators and cough control therapy for refractory or unexplained chronic cough: the FORTITUDE trial protocol. [PDF]
Kum E +21 more
europepmc +1 more source

